Evidence map›Paper›PMID 31822306›Full record

ArticleJournal of the International Neuropsychological Society : JINS2020

Sex Differences in Cognitive Changes in De Novo Parkinson's Disease.

Ece Bayram, Sarah J Banks, Guogen Shan, Nikki Kaplan, Jessica Z K Caldwell

Open access · greenAbstract read
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  7. Review
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  10. Partial correlation coefficient for a study with repeated measurements.Statistics in biopharmaceutical research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ece BayramDepartment of Neurosciences, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-6875-4242
Sarah J BanksDepartment of Neurosciences, University of California San Diego, La Jolla, CA, USA.
Guogen ShanDepartment of Environmental and Occupational Health, University of Nevada Las Vegas, Las Vegas, NV, USA.
Nikki KaplanLou Ruvo Center for Brain Health, Cleveland Clinic, Las Vegas, NV, USA.
Jessica Z K CaldwellLou Ruvo Center for Brain Health, Cleveland Clinic, Las Vegas, NV, USA.
Cleveland Clinic · USUniversity of California San Diego · USUniversity of Nevada, Las Vegas · US

Funding

Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) CNTN - ResubmissionP20GM109025 · NIGMS · CLEVELAND CLINIC FOUNDATION · PI JESSICA KIRKLAND CALDWELL · 2015 to 2026
$22.8M
TRAINING PROGRAM IN EMOTION RESEARCHT32MH018931 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI Richard J Davidson · 1989 to 2026
$11.6M
Sex-specific cognitive expression and risk in preclinical Alzheimer's diseaseR01AG066088 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BANKS, SARAH · 2019 to 2023
$3.9M
NIA NIH HHS R01 AG066088NIGMS NIH HHS P20 GM109025NIMH NIH HHS T32 MH018931
6 · The paper itself

Abstract

objectiveTo evaluate the sex differences in cognitive course over 4 years in Parkinson's disease (PD) patients with and without mild cognitive impairment (MCI) compared to controls.

methodsFour-year longitudinal cognitive scores of 257 cognitively intact PD, 167 PD-MCI, and 140 controls from the Parkinson's Progression Markers Initiative were included. Longitudinal scores of men and women, and PD with and without MCI were compared.

resultsWomen had better verbal memory, men had better visuospatial function. There was no interaction between sex, diagnostic group, and/or time (4-year follow-up period).

conclusionsSex differences in cognitive course in de novo PD are similar to healthy aging. Cognitive decline rates in PD with and without MCI are similar for the first 4 years of PD.

Indexed as

Sex CharacteristicsAgedAged, 80 and overCognitive AgingCognitive DysfunctionFemaleHumansLongitudinal StudiesMaleMiddle AgedParkinson DiseaseCognitionDeclineLongitudinal studiesMemoryParkinson’s diseaseSex

Identifiers

PMID31822306
PMCPMC7282562
OpenAlexW2995543869

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.