ArticleRadiation oncology (London, England)2019
Dose reduction to organs at risk with deep-inspiration breath-hold during right breast radiotherapy: a treatment planning study.
Article in Radiation oncology (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical benefits of deep inspiration breath-hold in postoperative radiotherapy for right-sided breast cancer: a meta-analysis.BMC cancer · 2024Pooled it
- Reproducibility of repeated breathhold and impact of breathhold failure in whole breast and regional nodal irradiation in prone crawl position.Scientific reports · 2022Trial
- Mechanically-assisted non-invasive deep inspiration breath-hold (MANIV-DIBH): A first clinical application in paediatric radiotherapy.Technical innovations & patient support in radiation oncology · 2026Article
- Prospective monitoring of the clinical implementation of ultrahypofractionated whole-breast radiotherapy using electronic patient-reported outcome measures.Clinical and translational radiation oncology · 2026Article
- Comparative dosimetric analysis of deep inspiration breath-hold versus free breathing radiotherapy in lung cancer: special emphasis on cardiac and subcardiac structure protection.Technical innovations & patient support in radiation oncology · 2026Article
- Dosimetric comparison of IMRT and VMAT with deep inspiration breath hold or free breathing for right-sided whole breast irradiation.BMC cancer · 2026Article
- Deep inspiration breath-hold for breast cancer radiotherapy: a modelling study of targeted versus non-targeted strategy for clinical and operational optimisation.The Lancet regional health. Europe · 2026Article
- Article
- Enhanced calibration method for wall-mounted RGSC cameras: Mitigating baseline drift caused by CT couch sagging.PloS one · 2025Article
- Evaluation of the liver load index as a predictor of liver exposure in right breast radiotherapy.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025Article
- Technical feasibility of delivering a simultaneous integrated boost in partial breast irradiation.Physics and imaging in radiation oncology · 2024Article
- Deep inspirational breast hold (DIBH) for right breast irradiation: Improved sparing of liver and lung tissue.Clinical and translational radiation oncology · 2024Article
- Breast Volume Is a Predictor of Higher Heart Dose in Whole-Breast Supine Free-Breathing Volumetric-Modulated Arc Therapy Planning.Current oncology (Toronto, Ont.) · 2023Article
- Dose Volume and Liver Function Test Relationship following Radiotheraphy for Right Breast Cancer: A Multicenter Study.Current oncology (Toronto, Ont.) · 2023Article
- SGRT-based DIBH radiotherapy practice for right-sided breast cancer combined with RNI: A retrospective study on dosimetry and setup accuracy.Journal of applied clinical medical physics · 2023Article
- Application of tangent-arc technology for deep inspiration breath-hold radiotherapy in left-sided breast cancer.Frontiers in oncology · 2023Article
- First clinical experience with real-time portal imaging-based breath-hold monitoring in tangential breast radiotherapy.Physics and imaging in radiation oncology · 2022Article
- Development of deep learning chest X-ray model for cardiac dose prediction in left-sided breast cancer radiotherapy.Scientific reports · 2022Article
- External Beam Accelerated Partial Breast Irradiation in Early Breast Cancer and the Risk for Radiogenic Pneumonitis.Cancers · 2022Article
- Is cancer a prognostic factor for severe COVID-19, especially for breast cancer patients?Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique · 2022Review
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe addition of regional nodal radiation (RNI) to whole breast irradiation for high risk breast cancer improves metastases free survival and new data suggests it contributes additional benefit to overall survival. Deep inspiration breath hold (DIBH) has been shown to reduce cardiac and pulmonary dose in the context of left-sided disease treated with or without RNI, yet few studies have investigated its utility for right-breast cancer. This study investigates the potential advantages of DIBH in local and locoregional radiotherapy for right-sided breast cancer.
methodsFree-breathing (FB) and DIBH computed tomography datasets were obtained from twenty patients who previously underwent radiotherapy for left-sided breast cancer. Ten patients were retrospectively planned for whole right breast only irradiation and ten patients were planned for irradiation to the whole breast plus ipsilateral supra-clavicular (SC) nodes, with and without irradiation of the ipsilateral internal mammary nodes (IMN). Dose-volume metrics for the clinical target volume, lungs, heart, left anterior descending artery, right coronary artery (RCA) and liver were recorded. Differences between FB and DIBH plans were analysed using Wilcoxon signed-rank tests, with P < 0.05 considered statistically significant.
resultsDIBH increased the average total lung volume compared to FB in both breast only and breast plus RNI cohorts (P = 0.001). For the breast only group, there was no significant improvement in any ipsilateral lung dose-volume metric between FB and DIBH. However, for the breast plus RNI group, there was an improvement in ipsilateral lung mean dose (18.9 ± 3.2 Gy to 15.9 ± 2.3 Gy, P = 0.002) and V20Gy (45.3 ± 13.3% to 32.9 ± 9.4%, P = 0.002). In addition, DIBH significantly reduced the maximum dose to the RCA for RNI (11.6 ± 7.2 Gy to 5.6 ± 2.9 Gy, P = 0.03). Significant reductions in the liver V20Gy and maximum dose were observed in all cohorts during DIBH compared to FB.
conclusionsDIBH is a promising approach for right-breast radiotherapy with considerable sparing of normal tissue, particularly when the ipsilateral IMNs are also irradiated.
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