ArticleBMC microbiology2019
Diversity and bioactivities of fungal endophytes from Distylium chinense, a rare waterlogging tolerant plant endemic to the Three Gorges Reservoir.
Article in BMC microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Comprehensive analysis of the complete mitochondrial genome ofFrontiers in plant science · 2026Article
- Investigating the antimicrobial and anticancer potential of culturable fungal endophytes isolated from the stems of Kirkia acuminata Oliv.BMC microbiology · 2025Article
- Insights into the Lignocellulose-Degrading Enzyme System Based on the Genome Sequence ofInternational journal of molecular sciences · 2025Article
- Environmental Factors Drive the Biogeographic Pattern ofJournal of fungi (Basel, Switzerland) · 2024Article
- Antioxidant properties and L-asparaginase activities of endophytic fungi from Cymbidium orchids.Folia microbiologica · 2024Article
- Endophytic fungi: A future prospect for breast cancer therapeutics and drug development.Heliyon · 2024Review
- Community Structure and Diversity of Endophytic Fungi in CultivatedJournal of fungi (Basel, Switzerland) · 2024Article
- Endophytic bacterial community structure and diversity of the medicinal plant Mirabilis himalaica from different locations.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Article
- Methods used for the study of endophytic fungi: a review on methodologies and challenges, and associated tips.Archives of microbiology · 2022Review
- Beneficial and pathogenic plant-microbe interactions during flooding stress.Plant, cell & environment · 2022Review
- Exploring the anticancer activities of novel bioactive compounds derived from endophytic fungi: mechanisms of action, current challenges and future perspectives.American journal of cancer research · 2022Review
- Comparison of the Bulk and Rhizosphere Soil Prokaryotic Communities Between Wild and Reintroduced Manglietiastrum sinicum Plants, a Threatened Species with Extremely Small Populations.Current microbiology · 2021Article
- Medicinal potentialities and pathogenic profile of Lasiodiplodia genus.World journal of microbiology & biotechnology · 2021Review
- Current Insight into Culture-Dependent and Culture-Independent Methods in Discovering Ascomycetous Taxa.Journal of fungi (Basel, Switzerland) · 2021Review
- Insights into the Bioprospecting of the Endophytic Fungi of the Medicinal PlantJournal of fungi (Basel, Switzerland) · 2021Article
- Diversity, Phylogeny and Antagonistic Activity of Fungal Endophytes Associated with Endemic Species ofJournal of fungi (Basel, Switzerland) · 2021Article
- Extracts of endophytic fungi from leaves of selected Nigerian ethnomedicinal plants exhibited antioxidant activity.BMC complementary medicine and therapies · 2021Article
- Marine endophytic fungal metabolites: A whole new world of pharmaceutical therapy exploration.Heliyon · 2021Review
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe present study involves diversity and biological activities of the endophytic fungal community from Distylium chinense, a rare waterlogging tolerant plant endemic to the Three Gorges Reservoir. This study has been conducted hypothesizing that the microbial communities in the TGR area would contribute to the host plant tolerating a range of abiotic stress such as summer flooding, infertility, drought, salinity and soil erosion etc., and they may produce new metabolites, which may possess plentiful bioactive property, especially antioxidant activity. Therefore in the current study, the antioxidant, antimicrobial and anticancer activities of 154 endophytes recovered from D. chinense have been investigated. Furthermore, the active metabolites of the most broad-spectrum bioactive strain have also been studied.
resultsA total of 154 fungal endophytes were isolated from roots and stems. They were categorized into 30 morphotypes based on cultural characteristics and were affiliated with 27 different taxa. Among these, the most abundant fungal orders included Diaporthales (34.4%) and Botryosphaeriales (30.5%), which were predominantly represented by the species Phomopsis sp. (24.7%) and Neofusicoccum parvum (23.4%). Fermentation extracts were evaluated, screening for antioxidant, antimicrobial and anticancer activities. Among the 154 isolates tested, 99 (64.3%) displayed significant antioxidant activity, 153 (99.4%) exhibited inclusive antimicrobial activity against at least one tested microorganism and 27 (17.5%) showed exclusive anticancer activity against one or more cancer cell lines. Specifically, the crude extract of Irpex lacteus DR10-1 exhibited note-worthy bioactivities. Further chemical investigation on DR10-1 strain resulted in the isolation and identification of two known bioactive metabolites, indole-3-carboxylic acid (1) and indole-3-carboxaldehyde (2), indicating their potential roles in plant growth promotion and human medicinal value.
conclusionThese results indicated that diverse endophytic fungal population inhabits D. chinense. One of the fungal isolate DR10-1 (Irpex lacteus) exhibited significant antioxidant, antimicrobial and anticancer potential. Further, its active secondary metabolites 1 and 2 also showed antioxidant, antimicrobial and anticancer potential.
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