ArticleCirculation research2020
A Balance Between Intermediate Filaments and Microtubules Maintains Nuclear Architecture in the Cardiomyocyte.
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Article in Circulation research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
78 citing papers in PubMed, 109 citations in OpenAlex.
- The nucleus as a mechanobiological hub in muscle aging.Nucleus (Austin, Tex.) · 2026Review
- Nuclear envelope rupture and resealing: mechanisms, consequences, and disease implications.Biochemical Society transactions · 2026Review
- Differential cardiac remodelling: patterns of cardiomyocyte morphometry in multiple patient conditions.Cardiovascular research · 2026Article
- Rhythms of growth: unveiling the mechanobiology behind heart maturation.The Journal of physiology · 2026Review
- The cytoskeleton contributes to abnormal genome-lamina interactions in LMNA-deficient cardiomyocytes.The Journal of cell biology · 2026Article
- Viscoelasticity of the Heart: An Overview of Viscoelastic Measurements at Different Scales.Annual review of biomedical engineering · 2026Review
- Nuclear Lamins: A Molecular Bridge Coupling Extracellular Mechanical Cues to Intranuclear Signal Transduction and Gene Regulation.International journal of molecular sciences · 2026Review
- The roles of the microtubule cytoskeletal network in cardiac mechanobiology.Journal of cell science · 2026Review
- Proteins Lamin A and SUN1 are exclusively decreased in nuclear grade 4 clear cell renal cell carcinoma.Oncology letters · 2026Article
- Mechanical regulation of LINC complex function: structural basis, physiological roles, and disease mechanisms in transnuclear mechanotransduction.Frontiers in cell and developmental biology · 2026Review
- TRPV1 deletion in male mice alters cardiomyocyte ultrastructure without affecting baseline cardiac function.Scientific reports · 2025Article
- Article
- Early Cytoskeletal Remodeling Drives Hypertrophic Cardiomyopathy Pathogenesis inJournal of cardiovascular development and disease · 2025Article
- Cardiomyocyte Nuclear Pleomorphism in a Mouse Model of Inherited Hypertrophic Cardiomyopathy.Journal of cardiovascular development and disease · 2025Article
- Microtubule forces drive nuclear damage in LMNA cardiomyopathy.Nature cardiovascular research · 2025Article
- Molecular insights into the role of desmin intermediate filament network in chromatin landscape, cardiomyocyte differentiation, and maturation.Cell death & disease · 2025Article
- Plasma Proteomics Reveals Dysregulated Pathways Across the SpectrumCirculation. Genomic and precision medicine · 2025Article
- Review
- Reorganizing chromatin by cellular deformation.Current opinion in cell biology · 2024Review
- CommonCirculation. Genomic and precision medicine · 2024Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Julie HefflerFrom the Department of Physiology, Pennsylvania Muscle Institute, Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine (J.H., P.R., S.P., K.V., K.U., A.B., B.L.P.).
Parisha P ShahDepartment of Medicine, Cardiovascular Institute, Institute of Regenerative Medicine, and Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine (P.P.S., J.R., R.J.).
Patrick RobisonFrom the Department of Physiology, Pennsylvania Muscle Institute, Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine (J.H., P.R., S.P., K.V., K.U., A.B., B.L.P.).
Sai PhyoFrom the Department of Physiology, Pennsylvania Muscle Institute, Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine (J.H., P.R., S.P., K.V., K.U., A.B., B.L.P.).
Kimberly VelizFrom the Department of Physiology, Pennsylvania Muscle Institute, Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine (J.H., P.R., S.P., K.V., K.U., A.B., B.L.P.).
Keita UchidaFrom the Department of Physiology, Pennsylvania Muscle Institute, Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine (J.H., P.R., S.P., K.V., K.U., A.B., B.L.P.).
Alexey BogushFrom the Department of Physiology, Pennsylvania Muscle Institute, Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine (J.H., P.R., S.P., K.V., K.U., A.B., B.L.P.).
Joshua RhoadesDepartment of Medicine, Cardiovascular Institute, Institute of Regenerative Medicine, and Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine (P.P.S., J.R., R.J.).
Rajan JainDepartment of Medicine, Cardiovascular Institute, Institute of Regenerative Medicine, and Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine (P.P.S., J.R., R.J.).
Benjamin L ProsserFrom the Department of Physiology, Pennsylvania Muscle Institute, Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine (J.H., P.R., S.P., K.V., K.U., A.B., B.L.P.).
University of Pennsylvania · USCalifornia Institute for Regenerative Medicine · USCardiovascular Institute of the South · US
Funding
TRAINING PROGRAM IN CELL AND MOLECULAR BIOLOGYT32GM007229 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BARTOLOMEI, MARISA S. · 1985 to 2023
$14.0MTraining Program in Cardiovascular Biology and MedicineT32HL007843 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI THOMAS P. CAPPOLA, Sharlene M Day · 1996 to 2026
$11.0MDetyrosinated microtubules in cardiomyocyte mechanicsR01HL133080 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Benjamin Lears Prosser · 2016 to 2026
$4.7MDeciphering Nuclear Lamina-Chromatin Organization in Cellular Competence and Cardiac DevelopmentDP2HL147123 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI JAIN, RAJAN · 2018 to 2018
$2.4MMechanical Regulation of Gene Expression in Ventricular MyocytesF31HL142238 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HEFFLER, JULIE · 2019 to 2021
$103kNHLBI NIH HHS DP2 HL147123NHLBI NIH HHS F31 HL142238NHLBI NIH HHS R01 HL133080NHLBI NIH HHS T32 HL007843NIGMS NIH HHS T32 GM007229
Abstract
PubMed holds no abstract for this paper.
Indexed as
Actin CytoskeletonAnimalsCells, CulturedDesminMaleMembrane ProteinsMiceMicrotubulesMyocytes, CardiacNuclear MatrixNuclear ProteinsRatsRats, Sprague-DawleyDesminMembrane Proteinsnesprin-3 protein, mouseNuclear Proteinscytoskeletondesmingenomemicrotubulesnucleus
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.