Evidence map›Paper›PMID 31821792›Full record

ArticleHormones and behavior2020

Combined HIV-1 Tat and oxycodone activate the hypothalamic-pituitary-adrenal and -gonadal axes and promote psychomotor, affective, and cognitive dysfunction in female mice.

Mohammed F Salahuddin, Alaa N Qrareya, Fakhri Mahdi, Dejun Jackson, Matthew Foster, Tamara Vujanovic, J Gaston Box, Jason J Paris

Open access · greenAbstract read
In one paragraph

Article in Hormones and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

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  16. Opioid and neuroHIV Comorbidity - Current and Future Perspectives.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mohammed F SalahuddinDepartment of BioMolecular Sciences, University of Mississippi, School of Pharmacy, University, MS 38677-1848, USA.
Alaa N QrareyaDepartment of BioMolecular Sciences, University of Mississippi, School of Pharmacy, University, MS 38677-1848, USA.
Fakhri MahdiDepartment of BioMolecular Sciences, University of Mississippi, School of Pharmacy, University, MS 38677-1848, USA.
Dejun JacksonDepartment of BioMolecular Sciences, University of Mississippi, School of Pharmacy, University, MS 38677-1848, USA.
Matthew FosterDepartment of BioMolecular Sciences, University of Mississippi, School of Pharmacy, University, MS 38677-1848, USA.
Tamara VujanovicDepartment of BioMolecular Sciences, University of Mississippi, School of Pharmacy, University, MS 38677-1848, USA.
J Gaston BoxDepartment of BioMolecular Sciences, University of Mississippi, School of Pharmacy, University, MS 38677-1848, USA.
Jason J ParisDepartment of BioMolecular Sciences, University of Mississippi, School of Pharmacy, University, MS 38677-1848, USA; Research Institute of Pharmaceutical Sciences, University of Mississippi, University, MS 38677, USA. Electronic address: parisj@olemiss.edu.
University of Mississippi · US

Funding

Pilot Project ProgramP30GM122733 · NIGMS · UNIVERSITY OF MISSISSIPPI · PI MAJUMDAR, SOUMYAJIT · 2018 to 2022
$5.3M
Opiate abuse and sex steroids influence neuroAIDS pathologyR00DA039791 · NIDA · UNIVERSITY OF MISSISSIPPI · PI PARIS, JASON RICHARD · 2017 to 2019
$734k
NIDA NIH HHS R00 DA039791NIGMS NIH HHS P30 GM122733
6 · The paper itself

Abstract

The majority of HIV

Indexed as

Neurotoxicity SyndromesAnimalsAnxietyCognitive DysfunctionDrug CombinationsFemaleGonadal Steroid HormonesGonadsHIV-1HIV InfectionsHumansHypothalamo-Hypophyseal SystemMiceMice, TransgenicMood DisordersOxycodoneDrug CombinationsGonadal Steroid HormonesOxycodonetat Gene Products, Human Immunodeficiency VirusBehavioral disinhibitionHPAHPGHuman immunodeficiency virusNovel object recognitionOpen fieldOpioidSH-SY5YTail suspensionTrans-activating transcriptor

Identifiers

PMID31821792
PMCPMC7071558
OpenAlexW2998422834

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.