ArticleMicrobial biotechnology2020
Raman-deuterium isotope probing to study metabolic activities of single bacterial cells in human intestinal microbiota.
Article in Microbial biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 67 citations in OpenAlex.
- Metabolic profiling of Escherichia coli under deuterium oxide-induced stress.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Review
- Ecology-microbiome engineering in Sauce-flavor Baijiu via Single-Cell Raman Spectroscopy.Biodesign research · 2026Review
- µ-Raman and GC-MS to interrogate the heterogeneity of deuterium-label incorporation on the single cell vs. fatty acid isotopologue level.Analytical and bioanalytical chemistry · 2026Article
- Rapid culture-free diagnosis of clinical pathogens via integrated microfluidic-Raman micro-spectroscopy.Nature communications · 2025Article
- Comparing Raman and NanoSIMS for heavy water labeling of single cells.Microbiology spectrum · 2025Article
- Resolving spatiotemporal dynamics in bacterial multicellular populations: approaches and challenges.Microbiology and molecular biology reviews : MMBR · 2025Review
- Raman Microspectroscopy to Trace the Incorporation of Deuterium from Labeled (Micro)Plastics into Microbial Cells.Analytical chemistry · 2025Article
- In situ degradation of 2-methylnaphthalene by a soil Penicillium strain associated with fungal-bacterial interactions.The ISME journal · 2025Article
- Towards high-accuracy bacterial taxonomy identification using phenotypic single-cell Raman spectroscopy data.ISME communications · 2025Article
- Antimicrobial Responses to Bacterial Metabolic Activity and Biofilm Formation Studied Using Microbial Fuel Cell-Based Biosensors.Biosensors · 2024Article
- Raman-Activated, Interactive Sorting of Isotope-Labeled Bacteria.Sensors (Basel, Switzerland) · 2024Article
- Raman-Activated Cell Ejection for Validating the Reliability of the Raman Fingerprint Database of Foodborne Pathogens.Foods (Basel, Switzerland) · 2024Article
- Multimodal imaging of metabolic activities for distinguishing subtypes of breast cancer.Biomedical optics express · 2023Article
- Advances and perspectives of using stable isotope probing (SIP)-based technologies in contaminant biodegradation.Water research X · 2023Article
- Deuterium- and Alkyne-Based Bioorthogonal Raman Probes for In Situ Quantitative Metabolic Imaging of Lipids within Plants.JACS Au · 2023Article
- Soil Thermophiles and Their Extracellular Enzymes: A Set of Capabilities Able to Provide Significant Services and Risks.Microorganisms · 2023Review
- Microbial Growth under Limiting Conditions-Future Perspectives.Microorganisms · 2023Review
- Review
- SRS-FISH: A high-throughput platform linking microbiome metabolism to identity at the single-cell level.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human intestinal microbiota is important to host health and is associated with various diseases. It is a challenge to identify the functions and metabolic activity of microorganisms at the single-cell level in gut microbial community. In this study, we applied Raman microspectroscopy and deuterium isotope probing (Raman-DIP) to quantitatively measure the metabolic activities of intestinal bacteria from two individuals and analysed lipids and phenylalanine metabolic pathways of functional microorganisms in situ. After anaerobically incubating the human faeces with heavy water (D
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.