Evidence map›Paper›PMID 31821694›Full record

ArticleChembiochem : a European journal of chemical biology2020

Calcium Regulates S100A12 Zinc Sequestration by Limiting Structural Variations.

Qian Wang, Aleksey Aleshintsev, Aneesha N Jose, James M Aramini, Rupal Gupta

Open access · greenAbstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Exploration (Beijing, China) · 2024
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Dynamic regulation of Zn(II) sequestration by calgranulin C.Protein science : a publication of the Protein Society · 2022
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Qian WangDepartment of Chemistry, College of Staten Island, City University of New York, 2800 Victory Boulevard, Staten Island, NY, 10314, USA.
Aleksey AleshintsevDepartment of Chemistry, College of Staten Island, City University of New York, 2800 Victory Boulevard, Staten Island, NY, 10314, USA.
Aneesha N JoseDepartment of Chemistry, College of Staten Island, City University of New York, 2800 Victory Boulevard, Staten Island, NY, 10314, USA.
James M AraminiStructural Biology Initiative, CUNY Advanced Science Research Center, 85 St. Nicholas Terrace, New York, NY, 10031, USA.
Rupal GuptaDepartment of Chemistry, College of Staten Island, City University of New York, 2800 Victory Boulevard, Staten Island, NY, 10314, USA.ORCID 0000-0001-8637-6129
The Graduate Center, CUNY · USCollege of Staten Island · US

Funding

Interdependence of Antimicrobial and Pro-inflammatory Activities Mediated byS100A12 in the Innate Immune ResponseR15GM131338 · NIGMS · COLLEGE OF STATEN ISLAND · PI GUPTA, RUPAL · 2019 to 2022
$936k
Upgrade of 800 MHz SpectrometerS10OD016432 · OD · NEW YORK STRUCTURAL BIOLOGY CENTER · PI PALMER, ARTHUR G · 2014 to 2014
$600k
NIGMS NIH HHS R15 GM131338NIH HHS S10 OD016432
6 · The paper itself

Abstract

Antimicrobial proteins such as S100A12 and S100A8/A9 are highly expressed and secreted by neutrophils during infection and participate in human immune response by sequestering transition metals. At neutral pH, S100A12 sequesters Zn

Indexed as

CalciumCobaltHumansHydrogen-Ion ConcentrationModels, MolecularProtein ConformationProtein MultimerizationS100A12 ProteinStructure-Activity RelationshipZincCalciumCobaltS100A12 ProteinS100A12 protein, humanZincNMR spectroscopynutritional immunityS100A12S100 metalloproteinszinc sequestration

Identifiers

PMID31821694
PMCPMC7376544
OpenAlexW2994806190

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.