Evidence map›Paper›PMID 31821553›Full record

ArticleJournal of neurochemistry2020

Activation of nicotinic acetylcholine receptors induces potentiation and synchronization within in vitro hippocampal networks.

Sarra Djemil, Xin Chen, Ziyue Zhang, Jisoo Lee, Mikael Rauf, Daniel T S Pak, Rhonda Dzakpasu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. The role of miRNA-144-3p/Oprk1/KOR in nicotine dependence and nicotine withdrawal in male rats.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Article
  3. ACh Transfers: Homeostatic Plasticity of Cholinergic Synapses.Cellular and molecular neurobiology · 2023
    Review
  4. Article
  5. CaScientific reports · 2022
    Article
  6. Review
  7. Article
  8. Effects of nicotine on DARPP-32 and CaMKII signaling relevant to addiction.Advances in pharmacology (San Diego, Calif.) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sarra DjemilDepartment of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA.ORCID 0000-0001-8622-650X
Xin ChenDepartment of Physics, Georgetown University, Washington, DC, USA.
Ziyue ZhangDepartment of Physics, Georgetown University, Washington, DC, USA.
Jisoo LeeDepartment of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA.
Mikael RaufDepartment of Human Science, Georgetown University Medical Center, Washington, DC, USA.
Daniel T S PakDepartment of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA.
Rhonda DzakpasuDepartment of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA.ORCID 0000-0002-7223-4602
Georgetown University · US

Funding

Translational Biomedical Science Training GrantTL1TR001431 · NCATS · GEORGETOWN UNIVERSITY · PI LEE, DEXTER L, SANDBERG, KATHRYN L · 2015 to 2024
$4.8M
Regulation of APP processing in synaptic plasticity and Alzheimer's diseaseRF1AG056603 · NIA · GEORGETOWN UNIVERSITY · PI PAK, DANIEL T · 2017 to 2018
$2.0M
NCATS NIH HHS TL1 TR001431NIA NIH HHS RF1 AG056603NIA NIH HHS RF1 AG056603-01NIA NIH HHS TL1 TR001431-01
6 · The paper itself

Abstract

Nicotinic acetylcholine receptors (nAChRs) are known to play a role in cognitive functions of the hippocampus, such as memory consolidation. Given that they conduct Ca

Indexed as

AnimalsCells, CulturedDose-Response Relationship, DrugFemaleHippocampusLong-Term PotentiationNerve NetNicotineNicotinic AgonistsPregnancyRatsRats, Sprague-DawleyReceptors, NicotinicNicotineNicotinic AgonistsReceptors, Nicotinicin vitro hippocampal networksmicro-electrode arraysneural network dynamicsnicotinenicotinic acetylcholine receptors

Identifiers

PMID31821553
PMCPMC7239735
OpenAlexW2995327934

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.