Observational studyEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2020
False lumen ejection fraction predicts growth in type B aortic dissection: preliminary results.
Observational study in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 72 citations in OpenAlex.
- Haemodynamic Predictors of Early Aortic Growth in Uncomplicated Type B Dissection: A Cohort Study.Interdisciplinary cardiovascular and thoracic surgery · 2026Observational
- False Lumen Haemodynamics in Type B Aortic Dissection: An in Vitro Study Using PIV and Patient-Specific Flexible Phantoms.Annals of biomedical engineering · 2026Article
- Spectral Computed Tomography for the Detection and Characterization of Communications Between the True and the False Lumen in Aortic Dissections.Investigative radiology · 2026Article
- Distal anastomotic new entry tears predict long-term outcomes after hemi-arch repair for DeBakey I aortic dissection†.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025Article
- Mechanisms of aortic dissection: From pathological changes to experimental andProgress in materials science · 2025Article
- Predicting Late Adverse Events in Uncomplicated Stanford Type B Aortic Dissection: Results From the ROADMAP Validation Study.Circulation. Cardiovascular imaging · 2025Article
- Evaluation of Aortic Diseases Using Four-Dimensional Flow Magnetic Resonance Imaging.Vascular specialist international · 2024Review
- Clinical Imaging and Innovations in Aortic Aneurysm and Dissection.Seminars in interventional radiology · 2024Review
- False lumen hemodynamics and partial thrombosis in chronic aortic dissection of the descending aorta.European radiology · 2024Article
- Hemodynamic predictors of negative false lumen remodeling after frozen elephant trunk for acute aortic dissection.General thoracic and cardiovascular surgery · 2024Observational
- Aortic remodelling based on false lumen communications in patients undergoing acute type I dissection repair with AMDS hybrid prosthesis: a substudy of the DARTS trial.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024Article
- Morphologic prognostic factor for thoracoabdominal aortic dilation after acute type A dissection repair.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- The Role of Multiple Re-Entry Tears in Type B Aortic Dissection Progression: A Longitudinal Study Using a Controlled Swine Model.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2024Article
- Interval changes in four-dimensional flow-derived in vivo hemodynamics stratify aortic growth in type B aortic dissection patients.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024Article
- Hemodynamic parameters impact the stability of distal stent graft-induced new entry.Scientific reports · 2023Article
- The Influence of Minor Aortic Branches in Patient-Specific Flow Simulations of Type-B Aortic Dissection.Annals of biomedical engineering · 2023Article
- Aortic Hemodynamics with Accelerated Dual-Venc 4D Flow MRI in Type B Aortic Dissection.Applied sciences (Basel, Switzerland) · 2023Article
- Entry Tear Hemodynamics Detect Patients With Adverse Aorta-Related Outcomes in Type B Aortic Dissection.JACC. Cardiovascular imaging · 2023Article
- Abdominal applications of quantitative 4D flow MRI.Abdominal radiology (New York) · 2022Review
- A three-dimensional biomodel of type A aortic dissection for endovascular interventions.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2022Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivesCurrent risk assessment strategies in type B aortic dissection are focused on anatomic parameters, although haemodynamic abnormalities that result in false lumen (FL) pressurization are thought to play a significant role in aortic growth. The objective of this study was to evaluate blood flow of the FL using 4D flow magnetic resonance imaging (MRI) and identify haemodynamic and anatomic factors that independently predict the rate of aortic growth.
methodsPatients with dissection of the descending thoraco-abdominal aorta (n = 18) were enrolled in a prospective observational study and underwent 4D flow MRI for haemodynamic assessment of the entry tear and FL. Anatomic parameters were obtained by magnetic resonance angiography and baseline computed tomography. False lumen ejection fraction (FL EF) was defined the ratio of retrograde flow rate at the dominant entry tear during diastole over the antegrade systolic flow rate.
resultsThe median aortic growth rate was 3.5 mm/year (interquartile range 0.5-8.1 mm/year). Entry tear peak velocity was lower in patients with enlarging aortic dimensions (95.5 ± 24.1 vs 128.1 ± 37.4 cm/s, P = 0.039). After adjusting for co-variates FL EF (β = 0.15, P = 0.004), baseline maximal aortic diameter (β = 0.37, P = 0.001) and the entry tear distance from the left subclavian artery (β = 0.07, P = 0.016) were significant predictors of aortic growth rate.
conclusionsBeyond standard anatomic risk factors, FL EF is an independent predictor of aortic growth rate and may represent an intuitive, non-invasive method to estimate FL pressurization and improve patient-specific risk assessment in patients with type B aortic dissection.
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