Evidence map›Paper›PMID 31821146›Full record

ArticleeLife2019

Dzip1 and Fam92 form a ciliary transition zone complex with cell type specific roles in

Jean-André Lapart, Marco Gottardo, Elisabeth Cortier, Jean-Luc Duteyrat, Céline Augière, Alain Mangé, Julie Jerber, Jérôme Solassol, Jay Gopalakrishnan, Joëlle Thomas and 1 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Genetic mutation ofLife science alliance · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Ciliogenesis membrane dynamics and organization.Seminars in cell & developmental biology · 2023
    Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Jean-André LapartInstitut NeuroMyoGène, CNRS UMR 5310, INSERM U1217, Université Claude Bernard Lyon 1, Lyon, France.ORCID 0000-0001-9167-8391
Marco GottardoInstitute of Human Genetics, Universitätsklinikum Düsseldorf, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.
Elisabeth CortierInstitut NeuroMyoGène, CNRS UMR 5310, INSERM U1217, Université Claude Bernard Lyon 1, Lyon, France.
Jean-Luc DuteyratInstitut NeuroMyoGène, CNRS UMR 5310, INSERM U1217, Université Claude Bernard Lyon 1, Lyon, France.
Céline AugièreInstitut NeuroMyoGène, CNRS UMR 5310, INSERM U1217, Université Claude Bernard Lyon 1, Lyon, France.
Alain MangéIRCM, INSERM, Université de Montpellier, ICM, Montpellier, France.ORCID 0000-0002-1566-9407
Julie JerberInstitut NeuroMyoGène, CNRS UMR 5310, INSERM U1217, Université Claude Bernard Lyon 1, Lyon, France.
Jérôme SolassolIRCM, INSERM, Université de Montpellier, ICM, Montpellier, France.
Jay GopalakrishnanInstitute of Human Genetics, Universitätsklinikum Düsseldorf, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.
Joëlle Thomas *Institut NeuroMyoGène, CNRS UMR 5310, INSERM U1217, Université Claude Bernard Lyon 1, Lyon, France.ORCID 0000-0002-0461-6131
Bénédicte Durand *Institut NeuroMyoGène, CNRS UMR 5310, INSERM U1217, Université Claude Bernard Lyon 1, Lyon, France.ORCID 0000-0002-8530-0613
Université Claude Bernard Lyon 1 · FRDüsseldorf University Hospital · DEInserm · FR

Funding

Agence Nationale de la Recherche DIVERCILFondation pour la Recherche Médicale FRM DEQ20131029168Université Claude Bernard Lyon 1 PhD Fellowship
6 · The paper itself

Abstract

Cilia and flagella are conserved eukaryotic organelles essential for cellular signaling and motility. Cilia dysfunctions cause life-threatening ciliopathies, many of which are due to defects in the transition zone (TZ), a complex structure of the ciliary base. Therefore, understanding TZ assembly, which relies on ordered interactions of multiprotein modules, is of critical importance. Here, we show that

Indexed as

AllelesAnimalsBasal BodiesCarrier ProteinsCation Transport ProteinsCell MembraneCiliaDrosophilaDrosophila ProteinsFlagellaGerm CellsMaleNuclear ProteinsSensory Receptor CellsSpermatogenesisCarrier ProteinsCation Transport ProteinsCby protein, DrosophilaDrosophila ProteinsNuclear ProteinsZip42C.1 protein, Drosophilabasal bodycell biologyciliaciliopathiesdevelopmental biologyD. melanogaster

Identifiers

PMID31821146
PMCPMC6904220
OpenAlexW2995396845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.