Evidence map›Paper›PMID 31821002›Full record

ArticleJournal of proteome research2020

Host Metabolic Response in Early Lyme Disease.

Bryna L Fitzgerald, Claudia R Molins, M Nurul Islam, Barbara Graham, Petronella R Hove, Gary P Wormser, Linden Hu, Laura V Ashton, John T Belisle

Open access · greenAbstract read
In one paragraph

Article in Journal of proteome research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Insights From Omics in Lyme Disease.The Journal of infectious diseases · 2024
    Review
  6. Article
  7. Review
  8. Review
  9. Current Knowledge in Skin Metabolomics: Updates from Literature Review.International journal of molecular sciences · 2022
    Review
  10. Article
  11. Lyme Disease: A Role for Coenzyme Q10 Supplementation?Antioxidants (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Article
  14. Redox Imbalance and Its Metabolic Consequences in Tick-Borne Diseases.Frontiers in cellular and infection microbiology · 2022
    Review
  15. Metabolic Response in Patients With Post-treatment Lyme Disease Symptoms/Syndrome.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  16. AnInfection and immunity · 2021
    Article
  17. Discovery and Surveillance of Tick-Borne Pathogens.Journal of medical entomology · 2021
    Article
  18. Article
  19. Review
  20. Comprehensive Mapping of the Cell Response toFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Bryna L FitzgeraldCenters for Disease Control and Prevention , Fort Collins , Colorado 80521 , United States.ORCID 0000-0002-8744-5795
Claudia R MolinsCenters for Disease Control and Prevention , Fort Collins , Colorado 80521 , United States.
M Nurul IslamDepartment of Microbiology, Immunology, and Pathology , Colorado State University , Fort Collins , Colorado 80521 , United States.
Barbara GrahamDepartment of Microbiology, Immunology, and Pathology , Colorado State University , Fort Collins , Colorado 80521 , United States.
Petronella R HoveDepartment of Microbiology, Immunology, and Pathology , Colorado State University , Fort Collins , Colorado 80521 , United States.
Gary P WormserDivision of Infectious Diseases, Department of Medicine , New York Medical College , Valhalla , New York 10595 , United States.
Linden HuSackler School of Graduate Biomedical Sciences , Tufts University School of Medicine , Boston , Massachusetts 02111 , United States.
Laura V AshtonCenters for Disease Control and Prevention , Fort Collins , Colorado 80521 , United States.
John T BelisleDepartment of Microbiology, Immunology, and Pathology , Colorado State University , Fort Collins , Colorado 80521 , United States.ORCID 0000-0002-2539-2798
Colorado State University · USCenters for Disease Control and Prevention · USNew York Medical College · USTufts University · US

Funding

Host Metabolic Biosignatures for the Diagnosis of Lyme DiseaseR01AI141656 · NIAID · COLORADO STATE UNIVERSITY · PI BELISLE, JOHN T · 2019 to 2023
$4.2M
Metabolic biomarkers and biosignatures for improved diagnosis of Lyme diseaseR33AI100228 · NIAID · COLORADO STATE UNIVERSITY · PI BELISLE, JOHN T · 2014 to 2016
$1.4M
NIAID NIH HHS R01 AI141656NIAID NIH HHS R33 AI100228
6 · The paper itself

Abstract

Lyme disease is a tick-borne bacterial illness that occurs in areas of North America, Europe, and Asia. Early infection typically presents as generalized symptoms with an erythema migrans (EM) skin lesion. Dissemination of the pathogen

Indexed as

Lyme DiseaseLyme NeuroborreliosisAsiaChromatography, LiquidEuropeHumansTandem Mass Spectrometryacylcarnitinebile acidBorrelia burgdorferieicosanoidglycerophospholipidlyme diseasemass spectrometrymetabolomicssphingolipid

Identifiers

PMID31821002
PMCPMC7262776
OpenAlexW2996533587

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.