Evidence map›Paper›PMID 31820841›Full record

Trial reportGeriatrics & gerontology international2020

Assessing the association between optimal energy intake and all-cause mortality in older patients with diabetes mellitus using the Japanese Elderly Diabetes Intervention Trial.

Takuya Omura, Yoshiaki Tamura, Takuya Yamaoka, Yukio Yoshimura, Takashi Sakurai, Hiroyuki Umegaki, Chiemi Kamada, Satoshi Iimuro, Yasuo Ohashi, Hideki Ito and 2 more

Open access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Geriatrics & gerontology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
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  3. Individualized treatment of diabetes mellitus in older adults.Geriatrics & gerontology international · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Takuya OmuraDepartment of Diabetes, Metabolism and Endocrinology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.ORCID https://orcid.org/0000-0001-5490-8653
Yoshiaki TamuraDepartment of Diabetes, Metabolism and Endocrinology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.
Takuya YamaokaDepartment of Diabetes, Metabolism and Endocrinology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.
Yukio YoshimuraTraining Department of Administrative Dietitians, Faculty of Human Life Science, Shikoku University, Tokushima, Japan.
Takashi SakuraiCenter for Comprehensive Care and Research on Demented Disorders, National Center for Geriatrics and Gerontology, Aichi, Japan.ORCID https://orcid.org/0000-0002-2369-3095
Hiroyuki UmegakiDepartment of Community Healthcare and Geriatric Medicine, Nagoya University, Nagoya, Japan.ORCID https://orcid.org/0000-0003-2504-4133
Chiemi KamadaTraining Department of Administrative Dietitians, Faculty of Human Life Science, Shikoku University, Tokushima, Japan.
Satoshi IimuroInnovation and Research Support Center, International University of Health and Welfare, Tokyo, Japan.
Yasuo OhashiDepartment of Integrated Science and Engineering for Sustainable Society, Chuo University, Tokyo, Japan.
Hideki ItoDepartment of Diabetes, Metabolism and Endocrinology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.
Atsushi ArakiDepartment of Diabetes, Metabolism and Endocrinology, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.
Japanese Elderly Diabetes Intervention Trial Research Group
Tokyo Metropolitan Geriatric Hospital · JPShikoku University · JPChuo University · JPInternational University of Health and Welfare · JPNagoya University Hospital · JPNational Center for Geriatrics and Gerontology · JP

Funding

Ministry of Health, Labor and WelfareResearch Grants for Longevity Sciences from the Ministry of Health, Labour and Welfare and the Japan Foundation for Aging and Health H12-Choju-016Research Grants for Longevity Sciences from the Ministry of Health, Labour and Welfare and the Japan Foundation for Aging and Health H15-Choju-016Research Grants for Longevity Sciences from the Ministry of Health, Labour and Welfare and the Japan Foundation for Aging and Health H17-Choju-Ordinathe Japan Foundation
6 · The paper itself

Abstract

aimSelecting optimal energy intake during diet therapy for older patients with diabetes mellitus is difficult because of the large differences in physical function and comorbid diseases. In Japan, although requirements for total energy intake are calculated by multiplying a person's standard bodyweight (BW) by the amount of physical activity, evidence supporting the application of this method among older people is limited. Therefore, we aimed to assess optimal energy intake by evaluating the relationship between energy intake and mortality in older patients.

methodsWe evaluated data from a 6-year prospective follow up of 756 older patients with diabetes mellitus, and the association between baseline nutrient intake and mortality. Total energy intake and nutrients were evaluated, and energy intake per actual BW was categorized into quartiles (Q). Cox regression analysis was used for statistical analyses. Energy intake per standard BW or age-related target BW was statistically analyzed using the same protocol.

resultsAnalysis of energy intake per actual BW showed that hazard ratios for mortality was significantly higher in Q1 and Q4. Similar associations were found for energy intake per standard or target BW. Subgroup analysis showed that mortality rate was the lowest in Q2 in the young-old population and in Q3 in the old-old population.

conclusionsA U-shaped relationship was observed between energy intake per BW and mortality in older patients with diabetes mellitus, which suggests that the optimal energy intake per actual or target BW should encompass a wide range to prevent malnutrition and excessive nutrition in these patients. Geriatr Gerontol Int 2020; 20: 59-65.

Indexed as

Energy IntakeAgedBody Mass IndexBody WeightDiabetes Mellitus, Type 2ExerciseFemaleFollow-Up StudiesHumansJapanMaleMortalityProportional Hazards ModelsProspective StudiesRegression Analysisbodyweightdiet therapyelderly diabetes mellitusenergy intakemortality

Identifiers

PMID31820841
PMCPMC7003876
OpenAlexW2995861332

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.