Evidence map›Paper›PMID 31820795›Full record

ReviewSocial cognitive and affective neuroscience2020

Neurobiological changes during the peripartum period: implications for health and behavior.

Emilia F Cárdenas, Autumn Kujawa, Kathryn L Humphreys

Abstract readReview
In one paragraph

Review in Social cognitive and affective neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Maternal peripartum stress: A new consensus-based definition.Archives of women's mental health · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Social Behavior and Neurogenesis.International journal of molecular sciences · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Prenatal Stress and Maternal Role in Neurodevelopment.Annual review of developmental psychology · 2024
    Article
  20. Interoception in pregnancy: Implications for peripartum depression.Neuroscience and biobehavioral reviews · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emilia F CárdenasDepartment of Psychology and Human Development, Vanderbilt University, 37203, Nashville, USA.
Autumn KujawaDepartment of Psychology and Human Development, Vanderbilt University, 37203, Nashville, USA.
Kathryn L HumphreysDepartment of Psychology and Human Development, Vanderbilt University, 37203, Nashville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy and the transition to parenthood is an important period marked by dramatic neurobiological and psychosocial changes that may have implications for the health of women and offspring. Although human and non-human animal research suggests that the brain undergoes alterations during the peripartum period, these changes are poorly understood. Here, we review existing research, particularly human neuroimaging and psychophysiological research, to examine changes in brain structure and function during the peripartum period and discuss potential implications for the health of women and offspring. First, we discuss the potential causes of these changes across pregnancy, including physiological and psychosocial factors. Next, we discuss the evidence for structural and functional changes in the brain during pregnancy and into the postpartum period, noting the need for research conducted prospectively across human pregnancy. Finally, we propose potential models of individual differences in peripartum neurobiological changes (i.e. hypo-response, typical response, hyper-response) and emphasize the need to consider trajectories of change in addition to pre-existing factors that may predict maternal adjustment to parenthood. We suggest that the consideration of individual differences in neurobiological trajectories across pregnancy may contribute to a better understanding of risk for negative health and behavior outcomes for women and offspring.

Indexed as

BrainFemaleHumansMaternal BehaviorMaternal HealthPeripartum Periodbrain functionbrain structureneurobiologyperipartum mental healthpostpartum depression

Identifiers

PMID31820795
PMCPMC7657461

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.