Evidence map›Paper›PMID 31820410›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021

Uniformity of cardiac

Gemma Roberts, Jim J Lloyd, Elizabeth Jefferson, Joseph P M Kane, Rory Durcan, Sarah Lawley, George S Petrides, Kim Howe, Iftikhar Haq, John T O'Brien and 1 more

Abstract read
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. [The clinical value ofSheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Review
  4. Cardiac sympathetic innervation in Parkinson's disease versus multiple system atrophy.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Article
  5. Article
  6. Anger recall mental stress decreasesJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  7. Myocardial Sympathetic Innervation Imaging with MIBG in Dementia with Lewy Bodies.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gemma RobertsInstitute of Neuroscience, Newcastle University, Biomedical Research Building, Campus for Ageing and Vitality, Westgate Road, Newcastle upon Tyne, NE4 6BE, UK. gemma.roberts@newcastle.ac.uk.
Jim J LloydInstitute of Neuroscience, Newcastle University, Biomedical Research Building, Campus for Ageing and Vitality, Westgate Road, Newcastle upon Tyne, NE4 6BE, UK.
Elizabeth JeffersonNuclear Medicine Department, Leazes Wing, Royal Victoria Infirmary, Richardson Road, Newcastle upon Tyne, NE1 4LP, UK.
Joseph P M KaneCentre for Public Health, Queen's University Belfast, Royal Victoria Hospital, Belfast, BT12 6BA, UK.
Rory DurcanInstitute of Neuroscience, Newcastle University, Biomedical Research Building, Campus for Ageing and Vitality, Westgate Road, Newcastle upon Tyne, NE4 6BE, UK.
Sarah LawleyInstitute of Neuroscience, Newcastle University, Biomedical Research Building, Campus for Ageing and Vitality, Westgate Road, Newcastle upon Tyne, NE4 6BE, UK.
George S PetridesNuclear Medicine Department, Leazes Wing, Royal Victoria Infirmary, Richardson Road, Newcastle upon Tyne, NE1 4LP, UK.
Kim HoweNuclear Medicine Department, Leazes Wing, Royal Victoria Infirmary, Richardson Road, Newcastle upon Tyne, NE1 4LP, UK.
Iftikhar HaqCardiology Department, Royal Victoria Infirmary, Richardson Road, Newcastle upon Tyne, NE1 4LP, UK.
John T O'BrienDepartment of Psychiatry, University of Cambridge, Box 189, Level E4 Cambridge Biomedical Campus, Cambridge, CB2 0SP, UK.
Alan J ThomasInstitute of Neuroscience, Newcastle University, Biomedical Research Building, Campus for Ageing and Vitality, Westgate Road, Newcastle upon Tyne, NE4 6BE, UK.

Funding

Medical Research Council G1100540
6 · The paper itself

Abstract

introductionSome studies report that assessing regional

methods31 older adults with normal cognition, 15 Alzheimer's disease (AD), and 17 Dementia with Lewy bodies (DLB) patients were recruited. 5 individuals had previous myocardial infarction. Participants with sufficient cardiac uptake for regional SPECT analysis (29/31 controls, 15/15 AD, 5/17 DLB) had relative uptake pattern recorded. Controls were assessed for risk of future cardiovascular events using QRISK2, a validated online tool.

resultsIn controls uptake was reduced in the inferior wall (85%), apex (23%), septum (15%), and lateral wall (8%). AD and DLB showed similar patterns to controls. Lung or liver interference was present in 61% of cases. Myocardial infarction cases showed regional reductions in uptake, but normal/borderline planar uptake. In controls, there was no relationship between cardiovascular risk score and uptake pattern.

conclusionsSignificant variability of regional cardiac

Indexed as

AgedAged, 80 and overAlzheimer DiseaseFemaleHumansIodine RadioisotopesLewy Body DiseaseMaleMiddle AgedRadiopharmaceuticalsSensitivity and SpecificitySingle Photon Emission Computed Tomography Computed TomographyUnited KingdomIodine-123Iodine RadioisotopesRadiopharmaceuticalsCardiac MIBGcardiac MIBG uptake homogeneitySPECTSPECT artifactssympathetic innervation

Identifiers

PMID31820410
PMCPMC8648658

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.