ArticleSurgical endoscopy2020
Endoscopic resection of T1 colorectal cancer prior to surgery does not affect surgical adverse events and recurrence.
Article in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Additional staining for lymphovascular invasion is associated with increased estimation of lymph node metastasis in patients with T1 colorectal cancer: Systematic review and meta-analysis.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2024Pooled it
- Prior endoscopic resection does not affect the outcome of secondary surgery for T1 colorectal cancer, a systematic review and meta-analysis.International journal of colorectal disease · 2022Pooled it
- Predictive factors for isolated pulmonary metastasis in pathological T1 colorectal cancer following curative resection with lymph node dissection: a multicenter study.Surgery today · 2026Article
- Competing Mortality Redefines the Net Benefit of Additional Surgery After Endoscopic Resection for T1 Colorectal Cancer in Older Adults.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Review
- Surveillance and Surgical Salvage Treatment for Endoscopically Removed T1 Colorectal Cancers.Gut and liver · 2025Review
- The risk factors of lymph node metastasis in early colorectal cancer: a predictive nomogram and risk assessment.International journal of colorectal disease · 2024Article
- Vertical margin distance in T1 colorectal carcinoma resected by endoscopic submucosal dissection affects prognosis after additional surgery.International journal of colorectal disease · 2024Article
- Differentiation grade as a risk factor for lymph node metastasis in T1 colorectal cancer.DEN open · 2024Article
- Endoscopic resection alone as a potential treatment method for low-risk deep invasive T1 colorectal cancer.iGIE : innovation, investigation and insights · 2023Article
- Review
- Limited wedge resection for T1 colon cancer (LIMERIC-II trial) - rationale and study protocol of a prospective multicenter clinical trial.BMC gastroenterology · 2023Article
- Effects of prior endoscopic resection on recurrence in patients with T1 colorectal cancer who underwent radical surgery.International journal of colorectal disease · 2023Article
- Colonoscopy-Assisted Laparoscopic Wedge Resection for the Treatment of Suspected T1 Colon Cancer.Annals of surgical oncology · 2023Article
- Long-term outcomes after endoscopic versus surgical resection of T1 colorectal carcinoma.Surgical endoscopy · 2023Article
- Lymph node metastasis in T1 colorectal cancer with the only high-risk histology of submucosal invasion depth ≥ 1000 μm.International journal of colorectal disease · 2022Article
- Vertical tumor margin of endoscopic resection for T1 colorectal carcinoma affects the prognosis of patients undergoing additional surgery.Surgical endoscopy · 2022Article
- Risk Stratification of T1 Colorectal Cancer Metastasis to Lymph Nodes: Current Status and Perspective.Gut and liver · 2021Review
- The effect of non-curative endoscopic resection on cT1N0M0 colorectal carcinoma patients who underwent additional surgery.Surgical endoscopy · 2021Article
- Clinical significance of immunohistochemical lymphovascular evaluation to determine additional surgery after endoscopic submucosal dissection for colorectal T1 carcinoma.International journal of colorectal disease · 2021Article
- Risk factors and predictors of lymph nodes metastasis and distant metastasis in newly diagnosed T1 colorectal cancer.Cancer medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough a "no-touch isolation" technique is used in colorectal cancer surgery to reduce the risk of metastatic induction, endoscopic resection (ER) prior to surgery may work against this aim. This study evaluated the effects of initial ER on short- and long-term outcomes in T1 colorectal cancer.
methodsThis retrospective cohort study enrolled patients with pathological T1 colorectal cancer who underwent colorectal surgical resection at a Japanese tertiary cancer center between 2002 and 2012. A total of 548 eligible patients were divided into two groups: patients initially treated using surgical resection with lymph node dissection (LND) (primary group, n = 304) and patients treated using initial ER and additional surgical resection with LND (secondary group, n = 244). The inverse probability of treatment weighting (IPTW) method based on propensity score was used to compare postoperative complications and long-term recurrence.
resultsThe incidence of postoperative complications with Clavien-Dindo classification grade ≥ II was 10.9% and 7.4% in the primary and secondary groups, respectively (p = 0.16). Multivariate analysis with a logistic proportional hazard regression model using IPTW revealed no significant differences in postoperative complications between the two groups (p = 0.79). During a median follow-up after surgery of 61.4 months, recurrence was observed in 3 (1.0%) and 8 (3.3%) patients, respectively (p = 0.06). Multivariate analysis with a Cox proportional hazard regression model using IPTW revealed no significant differences in recurrence between the two groups (p = 0.07).
conclusionOur results suggest no significant adverse effects of initial ER prior to surgery on surgical complications and long-term recurrence in T1 colorectal cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.