ArticleHeart and vessels2020
Mineralocorticoid receptor antagonists lead to increased adenosine bioavailability and modulate contractile cardiac parameters.
Milla Marques Hermidorff, Leonardo Vinícius Monteiro de Assis, Joel Alves Rodrigues, Leôncio Lopes Soares, Milton Hércules Guerra Andrade, Antônio José Natali, Mauro Cesar Isoldi
Abstract read
In one paragraphArticle in Heart and vessels, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors at 3 institutions in 1 country.
Milla Marques Hermidorff *Cell Signaling Laboratory, Research Center in Biological Science, Institute of Exact and Biological Sciences, Federal University of Ouro Preto, Campus Morro do Cruzeiro, Ouro Preto, MG, 35400-000, Brazil.
Leonardo Vinícius Monteiro de Assis *Laboratory of Comparative Physiology of Pigmentation, Department of Physiology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-5209-0835 Joel Alves RodriguesLaboratory of Exercise Biology, Department of Physical Education, Federal University of Viçosa, Viçosa, Brazil.
Leôncio Lopes SoaresLaboratory of Exercise Biology, Department of Physical Education, Federal University of Viçosa, Viçosa, Brazil.
Milton Hércules Guerra AndradeLaboratory of Enzymology and Proteomics, Research Center in Biological Science, Institute of Exact and Biological Sciences, Federal University of Ouro Preto, Ouro Preto, Brazil.
Antônio José NataliLaboratory of Exercise Biology, Department of Physical Education, Federal University of Viçosa, Viçosa, Brazil.
Mauro Cesar IsoldiCell Signaling Laboratory, Research Center in Biological Science, Institute of Exact and Biological Sciences, Federal University of Ouro Preto, Campus Morro do Cruzeiro, Ouro Preto, MG, 35400-000, Brazil. mauroisoldi@hotmail.com.
Universidade Federal de Ouro Preto · BRUniversidade Federal de Viçosa · BRUniversidade de São Paulo · BR
Funding
FAPEMIG APQ-02112-10 and APQ 00793-13FAPESP 2013/24337-4FAPESP 2018/16511-8
6 · The paper itselfAbstract
Activation of mineralocorticoid receptor antagonists (MRAs) is cardioprotective; however, this property is lost upon blockade or inactivation of adenosine (ADO) receptor A
Indexed as
5'-NucleotidaseAdenosineAdenosine DeaminaseAnimalsCalcium SignalingEplerenoneGPI-Linked ProteinsMaleMembrane ProteinsMineralocorticoid Receptor AntagonistsMyocardial ContractionMyocytes, CardiacRats, WistarReceptor, Adenosine A1Receptor, Adenosine A3Spironolactone5'-NucleotidaseAda protein, ratAdenosineAdenosine DeaminaseEplerenoneGPI-Linked ProteinsMembrane ProteinsMineralocorticoid Receptor AntagonistsNt5e protein, ratReceptor, Adenosine A1Receptor, Adenosine A3SpironolactoneAdenosine bioavailabilityand eplerenoneCardiac contractilityCardioprotectionRapid effects of aldosteronespironolactoneSpironolactone and eplerenone
Identifiers
PMID31820090
OpenAlexW2992927196
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