ArticleMicrobial ecology2020
Photoperiod Manipulation Affects Transcriptional Profile of Genes Related to Lipid Metabolism and Apoptosis in Zebrafish (Danio rerio) Larvae: Potential Roles of Gut Microbiota.
Article in Microbial ecology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of m.5178C>A variant with serum lipid levels: a systematic review and meta-analysis.Bioscience reports · 2021Pooled it
- Photoperiod driven modulation of behavior, gut microbiota, and brain transcriptomics in zebrafish.Pflugers Archiv : European journal of physiology · 2026Article
- Does the manipulation of light conditions affect the gut microbiome of Eurasian perch (Perca fluviatilis L.) in a recirculating aquaculture system?Journal of fish biology · 2026Article
- Rhythmic light exposure during incubation enhances liver development and lipid accumulation in chicken embryos.Animal bioscience · 2026Article
- Temperature and photoperiod stress in zebrafish larvae: impacts on development, gene regulation and PGC migration.Fish physiology and biochemistry · 2025Article
- Unraveling the significance of AGPAT4 for the pathogenesis of endometriosis via a multi-omics approach.Human genetics · 2024Article
- Gut Microbiota Alleviates Intestinal Injury Induced by Extended Exposure to Light via Inhibiting the Activation of NLRP3 Inflammasome in Broiler Chickens.International journal of molecular sciences · 2024Article
- Effects of simulated winter short photoperiods on the microbiome and intestinal metabolism in Huanghe carp (Frontiers in endocrinology · 2023Article
- Fat storage-inducing transmembrane proteins: beyond mediating lipid droplet formation.Cellular & molecular biology letters · 2022Review
- Time-Restricted Feeding Could Not Reduce Rainbow Trout Lipid Deposition Induced by Artificial Night Light.Metabolites · 2022Article
- Bifidobacterium lactis BL-99 modulates intestinal inflammation and functions in zebrafish models.PloS one · 2022Article
- About Welfare and Stress in the Early Stages of Fish.Frontiers in veterinary science · 2021Article
- Gut microbiota and metabolic marker alteration following dietary isoflavone-photoperiod interaction.Endocrinology, diabetes & metabolism · 2021Article
- Deep Insights into Gut Microbiota in Four Carnivorous Coral Reef Fishes from the South China Sea.Microorganisms · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Gut microbiota plays a fundamental role in maintaining host's health by controlling a wide range of physiological processes. Administration of probiotics and manipulation of photoperiod have been suggested as modulators of microbial composition and are currently undergoing an extensive research in aquaculture as a way to improve health and quality of harvested fish. However, our understanding regarding their effects on physiological processes is still limited. In the present study we investigated whether manipulation of photoperiod and/or probiotic administration was able to alter microbial composition in zebrafish larvae at hatching stage. Our findings show that probiotic does not elicit effects while photoperiod manipulation has a significant impact on microbiota composition. Moreover, we successfully predicted lipid biosynthesis and apoptosis to be modulated by microbial communities undergoing continuous darkness. Interestingly, expression levels of caspase 3 gene (casp3) and lipid-related genes (hnf4a, npc1l1, pparγ, srebf1, agpat4 and fitm2) were found to be significantly overexpressed in dark-exposed larvae, suggesting an increase in the occurrence of apoptotic processes and a lipid metabolism impairment, respectively (p < 0.05). Our results provide the evidence that microbial communities in zebrafish at early life stages are not modulated by a short administration of probiotics and highlight the significant effect that dark photoperiod elicits on zebrafish microbiota and potentially on health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.