ArticleIntensive care medicine2020
Is tranexamic acid going to CRASH the management of traumatic brain injury?
Article in Intensive care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Tranexamic acid in the management of traumatic brain injury: a systematic review and meta-analysis with trial sequential analysis.Einstein (Sao Paulo, Brazil) · 2025Pooled it
- Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials.Intensive care medicine · 2021Pooled it
- Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial.Critical care (London, England) · 2020Trial
- Optimization of Patients Outcomes: Management Strategies for Polytrauma in the Neuro-ICU.Korean journal of neurotrauma · 2024Article
- Evaluation and Management of Traumatic Brain Injuries in the Pediatric Intensive Care Unit.Advances in neurobiology · 2024Review
- Perioperative Management of Polytrauma Patients with Severe Traumatic Brain Injury Undergoing Emergency Extracranial Surgery: A Narrative Review.Journal of clinical medicine · 2021Review
- Tranexamic acid in traumatic brain injury: systematic review and meta-analysis trumps a large clinical trial?Intensive care medicine · 2021Article
- Focus on neuro-critical care: combined interventions to improve relevant outcomes.Intensive care medicine · 2020Article
Corrections and comments
- Comment on
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
31820035What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.