Evidence map›Paper›PMID 31819908›Full record

ReviewEpilepsia open2019

Climate change and epilepsy: Time to take action.

Sanjay M Sisodiya, Hayley J Fowler, Iain Lake, Rosemary O Nanji, Kinga Gawel, Camila V Esguerra, Charles Newton, Aideen Foley

Open access · goldAbstract readReview
In one paragraph

Review in Epilepsia open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Stroke and climate change: A World Stroke Organization scientific statement.International journal of stroke : official journal of the International Stroke Society · 2026
    Review
  2. Article
  3. Medications, epilepsy and climate change: Added layers of complexity.British journal of clinical pharmacology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

Sanjay M SisodiyaDepartment of Clinical and Experimental Epilepsy UCL Queen Square Institute of Neurology London UK.ORCID https://orcid.org/0000-0002-1511-5893
Hayley J FowlerSchool of Civil Engineering and Geosciences Newcastle University Newcastle upon Tyne UK.
Iain LakeSchool of Environmental Sciences University of East Anglia Norwich UK.
Rosemary O NanjiCentre for Molecular Medicine Norway Faculty of Medicine and Department of Pharmacy Faculty of Mathematics and Natural Sciences University of Oslo Oslo Norway.
Kinga GawelCentre for Molecular Medicine Norway Faculty of Medicine and Department of Pharmacy Faculty of Mathematics and Natural Sciences University of Oslo Oslo Norway.
Camila V EsguerraCentre for Molecular Medicine Norway Faculty of Medicine and Department of Pharmacy Faculty of Mathematics and Natural Sciences University of Oslo Oslo Norway.ORCID https://orcid.org/0000-0002-2271-8094
Charles NewtonMedical Sciences Division University of Oxford Oxford UK.
Aideen FoleyDepartment of Geography Birkbeck College University of London London UK.
University of Oslo · NOBirkbeck, University of London · GBMedical University of Lublin · PLNational Hospital for Neurology and Neurosurgery · GBNewcastle University · GBUniversity of East Anglia · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Climate change is the biggest challenge facing humanity today. The associated global warming and humidification, increases in the severity and frequency of extreme climate events, extension of the ranges of vector-borne diseases, and the consequent social and economic stresses and disruption will have major negative consequences on many aspects of health care. People whose resilience to change is already impaired may suffer disproportionately from these environmental changes, which are of unprecedented reach and magnitude. There has been little connection made so far between climate change and epilepsy. We briefly review the history of climate change science and the subsequent response of the global scientific community. We consider how climate change effects might in general affect health and disease. We consider some of the underlying complex interactions that, for example, favor the spread of vector-borne diseases and how climate models operate and may help plan for global and local changes. We then speculate specifically on how these generic ideas may apply specifically to epilepsy. We consider these impacts at levels from molecular to the epidemiological. Data are sparse, and there is undoubtedly a need for more information to enable better estimation of possible effects of climate change on care in epilepsy. We also consider how the professional activities of those involved in epilepsy health care might contribute to global carbon emissions, for example, through flying for conference attendance. Healthcare organizations across the world are already considering, and responding to, many of these issues. We argue for more research in this area, but also for action today. Actions today are likely to generate cobenefits for health care, including care in epilepsy, resulting from efforts to decarbonize, mitigate effects of climate change that has already happened, and plan for adaptation to climate change.

Indexed as

antiepileptic drugbiodiversitygeneticglobal warminginfectionseizures

Identifiers

PMID31819908
PMCPMC6885657
OpenAlexW2972723611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.