ArticleJournal of advanced veterinary and animal research2019
Time dependent screening of antibiotic residues in milk of antibiotics treated cows.
Article in Journal of advanced veterinary and animal research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 40 citations in OpenAlex.
- Variations in cow milk and teat skin microbiota across the lactation cycle with intramammary cephalosporin use at dry-off.Applied and environmental microbiology · 2026Article
- Penicillin G and Cloxacillin in Costa Rican Dairy Products: Quantitative Analysis and Lactic Acid Bacteria Resistance Profiling.Antibiotics (Basel, Switzerland) · 2026Article
- Toxigenic and Antibiotic-ResistantMicroorganisms · 2025Article
- Surfactant-Based Polymer Microchip Electrophoresis of Ciprofloxacin Hydrochloride Monohydrate in Unfiltered Milk With Fluorescence Detection.Electrophoresis · 2025Article
- Residual antibiotics in milk samples: Assessing the risk and prevalence in Bangladesh.Heliyon · 2025Article
- Article
- Antibiotic Residues in Milk and Milk-Based Products Served in Kuwait Hospitals: Multi-Hazard Risk Assessment.Antibiotics (Basel, Switzerland) · 2024Article
- Nutrition, gastrointestinal microorganisms and metabolites in mastitis occurrence and control.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Review
- Tetracycline residues in fresh dairy milk from three districts in Indonesia: Occurrence and dietary exposure assessment.Veterinary world · 2023Article
- Screening and quantification of antibiotic residues in poultry products and feed in selected areas of Bangladesh.Veterinary world · 2023Article
- Antibiotic-resistant bacteria in bovine milk in India.Journal of advanced veterinary and animal research · 2023Article
- Screening of antibiotic residue in transported live fish and water collected from different fish markets in Mymensingh district of Bangladesh.Journal of advanced veterinary and animal research · 2022Article
- Antibiotic resistance and phylogenetic profiling ofCurrent research in microbial sciences · 2022Article
- Advances in therapeutic and managemental approaches of bovine mastitis: a comprehensive review.The veterinary quarterly · 2021Review
- Antimicrobial uses for livestock production in developing countries.Veterinary world · 2021Review
- 2-Methyl Nonyl Ketone FromFrontiers in chemistry · 2021Article
- Knowing Is Not Enough: A Mixed-Methods Study of Antimicrobial Resistance Knowledge, Attitudes, and Practises Among Maasai Pastoralists.Frontiers in veterinary science · 2021Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo analyze the presence of selective antibiotic residues (oxytetracycline, amoxicillin, and ciprofloxacin) in milk during the antibiotic treatment course, and to evaluate the thermal effect on antibiotics residual status in milk of antibiotic-treated cows. MATERIALS AND
methodsThe raw fresh milk was collected from 18 lactating cows before antibiotics treatment, which were brought to the veterinary hospital and suffered from either mastitis, foot and mouth disease, fever, local wound, or non-specific diarrhea, and so on. Out of the 18 lactating cows, six were treated with oxytetracycline, six were treated with amoxicillin, and six were treated with ciprofloxacin parenterally. Milk samples were also collected at 2nd day during treatment and final collection was done after maintaining the withdrawal period. Since milk is heated before consumption, it was boiled at 100°C for 20 min to evaluate the thermal effect on antibiotics residual status. Thin-layer chromatography was done for screening of antibiotics residue before and after boiling of the milk.
resultsAt day 0 (before antibiotic treatment), no antibiotics (oxytetracycline, ciprofloxacin and amoxicillin) residue was detected in raw milk of antibiotic treated cows. In contrast, on day 2 (during antibiotic treatment), 100% raw milk samples showed positive for antibiotics residue. After boiling, all milk samples showed positive for such specific antibiotics residue. On the other hand, no antibiotics residues were detected on day 9, which indicates the completion of the withdrawal period of the respective antibiotic. The intensities of bands for antibiotic on thin-layer chromatography plate of antibiotic residues in milk samples (oxytetracycline, amoxicillin, and ciprofloxacin) expressed that the respective antibiotic residual status was higher in the boiled milk compare to the raw milk.
conclusionProper maintenance of withdrawal period after antibiotic treatment would minimize the risk of antibiotic residues in milk, and boiling does not change these specific antibiotics residual status in milk. Therefore, awareness regarding the proper maintenance of withdrawal period after antibiotic treatment in lactating cows is one of the best strategies that may positively reduce the risk of antimicrobial drugs residue in milk.
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