Evidence map›Paper›PMID 31819792›Full record

ArticleThe Pan African medical journal2019

Lassa virus RNA detection from suspected cases in Nigeria, 2011-2017.

Salu Olumuyiwa Babalola, James Ayorinde Babatunde, Orenolu Mercy Remilekun, Anyanwu Roosevelt Amaobichukwu, Abdullah Mariam Abiodun, Idris Jide, Abdus-Salam Ismail Adeshina, Ihekweazu Chikwe, Omilabu Sunday Aremu

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Article in The Pan African medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Salu Olumuyiwa BabalolaDepartment of Medical Microbiology and Parasitology, College of Medicine, University of Lagos (CMUL), PM.B. 12003, Lagos, Nigeria.
James Ayorinde BabatundeCentre for Human and Zoonotic Virology (CHAZVY), Central Research Laboratory, College of Medicine, University of Lagos (CMUL)/Lagos University Teaching Hospital (LUTH), Lagos, Nigeria.
Orenolu Mercy RemilekunCentre for Human and Zoonotic Virology (CHAZVY), Central Research Laboratory, College of Medicine, University of Lagos (CMUL)/Lagos University Teaching Hospital (LUTH), Lagos, Nigeria.
Anyanwu Roosevelt AmaobichukwuCentre for Human and Zoonotic Virology (CHAZVY), Central Research Laboratory, College of Medicine, University of Lagos (CMUL)/Lagos University Teaching Hospital (LUTH), Lagos, Nigeria.
Abdullah Mariam AbiodunCentre for Human and Zoonotic Virology (CHAZVY), Central Research Laboratory, College of Medicine, University of Lagos (CMUL)/Lagos University Teaching Hospital (LUTH), Lagos, Nigeria.
Idris JideHonourable Commissioner for Health, Lagos State Ministry of Health, Alausa, Ikeja, Lagos, Nigeria.
Abdus-Salam Ismail AdeshinaEpidemiology Unit, Directorate of Disease Control, Lagos State Ministry of Health, Alausa, Ikeja, Lagos, Nigeria.
Ihekweazu ChikweNigerian Centre for Disease Control (NCDC), Plot 801, Ebitu Ukiwe Street, Jabi, Abuja, Nigeria.
Omilabu Sunday AremuDepartment of Medical Microbiology and Parasitology, College of Medicine, University of Lagos (CMUL), PM.B. 12003, Lagos, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe diagnosis of Lassa fever is crucial to confirm cases, as well as to control/prevent nosocomial and community-based transmission and initiation of treatment, which is still limited in the country. Thus, we aimed at providing some information on the laboratory detection of Lassa from suspected cases in Nigeria.

methodsThis was a retrospective study of seasonal Lassa fever outbreaks data from 1,263 samples analyzed using Reverse Transcription-Polymerase Chain Reaction (RT-PCR) at the Virology Research Laboratory, College of Medicine, University of Lagos/Lagos University Teaching Hospital between year 2011 and 2017. Data were analyzed using the 21

resultsThe RT-PCR test confirmed the presence of Lassa in 112 (8.9%) comprising 61 (54.4%) males, 48 (42.9%) females and 3 (2.7%) individuals without gender information. Those aged between 18 and 49 years were mostly affected. There was a decline in the detection of Lassa from 4.7% in 2011/2012 to less than 1% by the 2014/2015. However, during the 2015/2016 and 2016/2017 seasons the detection rates increased to 10.4% and 15.1% respectively. The Northern region of Nigeria reported high confirmed cases of Lassa. The South Western region also witnessed an increased Lassa fever positivity rate of 13.4% of which Lagos and Ogun states being the focal state of Lassa activity in the region.

conclusionThese established the need for heightening the continued surveillance for Lassa as well as the establishment of other testing facilities within these endemic regions for prompt diagnosis of Lassa fever.

Indexed as

Disease OutbreaksAdolescentAdultAgedChildChild, PreschoolCross-Sectional StudiesFemaleHumansInfantLassa FeverLassa virusMaleMiddle AgedNigeriaRetrospective StudiesRNA, ViralendemicityLassa virus (LASV)public health burdenreverse transcription-polymerase chain reaction (RT-PCR)sensitization and health educationviral haemorrhagic fever (VHF)

Identifiers

PMID31819792
PMCPMC6884721

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.