Evidence map›Paper›PMID 31819767›Full record

ReviewExperimental and therapeutic medicine2019

Venous thromboembolism in cancer patients: Still looking for answers.

Roua Anamaria Iorga, Ovidiu Gabriel Bratu, Radu Dragos Marcu, Traian Constantin, Dan Liviu Dorel Mischianu, Bogdan Socea, Mihnea-Alexandru Gaman, Camelia Cristina Diaconu

Open access · diamondAbstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Can thromboprophylaxis build a link for cancer patients undergoing surgical and/or chemotherapy treatment? The MeTHOS cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Trial
  3. Article
  4. Article
  5. Improvement of thrombosis management in patients with cancer: a practical consensus document of recommendations for cancer-associated thrombosis patients' healthcare in Spain.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The association between two genetic polymorphisms inSaudi journal of biological sciences · 2022
    Article
  15. Review
  16. Review
  17. Portal vein thrombosis: A concise review (Review).Experimental and therapeutic medicine · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Roua Anamaria IorgaInternal Medicine Department, Clinical Emergency Hospital of Bucharest, 014461 Bucharest, Romania.
Ovidiu Gabriel BratuUrology Department, Emergency University Central Military Hospital, 010825 Bucharest, Romania.
Radu Dragos MarcuUrology Department, Emergency University Central Military Hospital, 010825 Bucharest, Romania.
Traian ConstantinUniversity of Medicine and Pharmacy 'Carol Davila', 050474 Bucharest, Romania.
Dan Liviu Dorel MischianuUrology Department, Emergency University Central Military Hospital, 010825 Bucharest, Romania.
Bogdan SoceaUniversity of Medicine and Pharmacy 'Carol Davila', 050474 Bucharest, Romania.
Mihnea-Alexandru GamanUniversity of Medicine and Pharmacy 'Carol Davila', 050474 Bucharest, Romania.
Camelia Cristina DiaconuInternal Medicine Department, Clinical Emergency Hospital of Bucharest, 014461 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROEmergency University · USClinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with cancer-associated venous thromboembolism (VTE) represent a real challenge in clinical practice. Patients with cancer have a greater risk both of VTE and bleeding. There are only a few studies regarding the therapeutic approach of VTE in patients with cancer, especially after cancer surgery, and on thromboprophylaxis during chemotherapy. Many of the anticoagulation therapy recommendations for cancer patients are extrapolated from trials that are not conducted in cancer cohorts. It is essential to assess the efficacy and safety of VTE prophylaxis in this particular subgroup, which bears higher risks both of VTE recurrence and major hemorrhagic events. The introduction of direct oral anticoagulants in everyday practice represented a major evolution of the anticoagulant treatment. Direct anticoagulants could represent a more appealing alternative to low-molecular-weight heparin in paraneoplastic venous thrombosis, due to the patient comfort, easy administration of the drug and emerging studies that prove similar efficacy and safety as the standard treatment. However, there is limited data on the treatment with direct oral anticoagulants in patients with paraneoplastic venous thromboembolism.

Indexed as

cancerdirect oral anticoagulantsheparinparaneoplasticvenous thromboembolism

Identifiers

PMID31819767
PMCPMC6895781
OpenAlexW2974916944

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.