Evidence map›Paper›PMID 31819622›Full record

ReviewCancer management and research2019

Benefits Of Timely Care In Pancreatic Cancer: A Systematic Review To Navigate Through The Contradictory Evidence.

Gábor Lukács, Árpád Kovács, Marcell Csanádi, Mariann Moizs, Imre Repa, Zoltán Kaló, Zoltán Vokó, János György Pitter

Abstract readReview
In one paragraph

Review in Cancer management and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Impact of Biopsy Attempts, Race, and Access on Time to Initiation of Treatment for Pancreatic Cancer.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Impact of SARS-CoV-2 pandemic on pancreatic cancer services and treatment pathways: United Kingdom experience.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2021
    Article
  17. Article
  18. The pancreas and COVID-19: a clinical conundrum.American journal of translational research · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gábor LukácsMóritz Kaposi General Hospital, Kaposvár, Hungary.
Árpád KovácsMóritz Kaposi General Hospital, Kaposvár, Hungary.
Marcell CsanádiSyreon Research Institute, Budapest, Hungary.
Mariann MoizsMóritz Kaposi General Hospital, Kaposvár, Hungary.
Imre RepaMóritz Kaposi General Hospital, Kaposvár, Hungary.
Zoltán KalóSyreon Research Institute, Budapest, Hungary.ORCID 0000-0001-7762-2607
Zoltán VokóSyreon Research Institute, Budapest, Hungary.
János György PitterSyreon Research Institute, Budapest, Hungary.ORCID 0000-0002-6784-9215

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evidence base of policies that improve the timeliness of cancer care is under ongoing debate. Pancreatic cancer is frequently diagnosed in a stage when curative therapy is not feasible; hence, it is an important target for timelier healthcare interventions. The objectives of our research were to identify all clinical studies on pancreatic cancer care delays via a systematic literature review, to assess the study methodologies for possible biases, to conclude on the available evidence, and to formulate research recommendations on evidence gaps. Nineteen studies were identified and eight reported multivariate analyses. Although many sources of bias shifted the results towards negative or paradoxical findings, a statistically significant association of shorter delays with better clinical outcomes was demonstrated in the majority of studies reporting multivariate analyses. Noninferiority analyses were not published. Further efforts to provide timely care for pancreatic cancer patients are encouraged, and studies on the associations of delay with patient experience and healthcare resource utilization are warranted.

Indexed as

biasdelaypancreatic cancerprognosissystematic reviewwait time

Identifiers

PMID31819622
PMCPMC6875504

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.