ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2019
Abdominal Fat Is Directly Associated With Inflammation In Persons With Type-2 Diabetes Regardless Of Glycemic Control - A Jordanian Study.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Association between body roundness index and suicidal ideation in U.S. adults: A cross-sectional study.Preventive medicine reports · 2025Article
- Reframing Diabetes Prevention: From Body Shaming to Metabolic Reprogramming.American journal of lifestyle medicine · 2025Review
- Association between cardiometabolic index and risk of testosterone deficiency in adult men: a cross-sectional study.BMC public health · 2025Article
- Firefighters Versus Law Enforcement Officers: A Comparison of Cardiovascular Disease Risk.International journal of exercise science · 2025Article
- Non-linear associations of cardiometabolic index with insulin resistance, impaired fasting glucose, and type 2 diabetes among US adults: a cross-sectional study.Frontiers in endocrinology · 2024Article
- Sex Differences in the Relationship between Abdominal Obesity and Cardiovascular Death in Elderly Patients with Permanent Pacemakers Implantation: A Retrospective Cohort Study.Evidence-based complementary and alternative medicine : eCAM · 2023Review
- The Relation between Eating Habits and Abdominal Fat, Anthropometry, PON1 and IL-6 Levels in Patients with Multiple Sclerosis.Nutrients · 2020Article
- Association Metabolic Obesity Phenotypes with Cardiometabolic Index, Atherogenic Index of Plasma and Novel Anthropometric Indices: A Link of FTO-rs9939609 Polymorphism.Vascular health and risk management · 2020Article
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Authors and funding
6 authors.
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Abstract
BACKGROUND AND
aimSystemic inflammation is related to the progression of complications associated with diabetes. This study aimed to investigate the association between general and abdominal obesity and inflammation in patients with type-2 diabetes with or without glycemic control.
methodsA total of 198 men (n=73) and women (n=125) diagnosed with type 2 diabetes participated in this study. General obesity markers, body mass index (BMI), and abdominal fat were assessed. Circulating concentrations of glycated hemoglobin (HbA1C), C-reactive protein (CRP), and serum interleukin-6 (IL-6) were determined. Poor glycemic control and good glycemic control were defined as having fasting HbA1C concentrations ≥7% and <7%, respectively. Multivariate adjusted analysis of covariance was used to determine the relation between BMI and abdominal fat and markers of inflammation in patients with good and poor glycemic control.
resultsPatients in <7% HbA1C category, those with high abdominal fat had ≈262% higher CRP and ≈30.6% higher IL-6 compared to those with low abdominal fat (
conclusionHigh level of abdominal fat is associated with systemic inflammation in type-2 diabetes regardless of glycemic control. Abdominal fat is a better predictor (determinant) of inflammation than BMI in patients with type-2 diabetes with or without glycemic control.
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