Evidence map›Paper›PMID 31819557›Full record

ArticleInfection and drug resistance2019

Diagnostic Accuracy of Interleukin-27 in Bronchoalveolar Lavage Fluids for Pulmonary Tuberculosis.

Shan Lin, Yan Wang, Yuhong Li, Di Xiao, Jin Guo, Weixiu Ma, Wenjing An, Hongqian Liu, Yingqing Shi, Lei Zhang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. The effects ofFrontiers in immunology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Shan Lin *Department of Respiratory Medicine, Qinghai University Affiliated Hospital, Xining 810001, People's Republic of China.ORCID 0000-0001-5163-6533
Yan Wang *Department of Respiratory Medicine, Qinghai University Affiliated Hospital, Xining 810001, People's Republic of China.
Yuhong LiDepartment of Respiratory Medicine, Qinghai University Affiliated Hospital, Xining 810001, People's Republic of China.
Di XiaoDepartment of Respiratory Medicine, Qinghai University Affiliated Hospital, Xining 810001, People's Republic of China.
Jin GuoDepartment of Respiratory Medicine, Qinghai University Affiliated Hospital, Xining 810001, People's Republic of China.
Weixiu MaDepartment of Respiratory Medicine, Qinghai University Affiliated Hospital, Xining 810001, People's Republic of China.
Wenjing AnDepartment of Respiratory Medicine, Qinghai University Affiliated Hospital, Xining 810001, People's Republic of China.
Hongqian LiuDepartment of Respiratory Medicine, Qinghai University Affiliated Hospital, Xining 810001, People's Republic of China.
Yingqing ShiDepartment of Respiratory Medicine, Qinghai University Affiliated Hospital, Xining 810001, People's Republic of China.
Lei ZhangDepartment of Respiratory Medicine, Qinghai University Affiliated Hospital, Xining 810001, People's Republic of China.
Jingxia Cui *Department of Respiratory Medicine, Qinghai University Affiliated Hospital, Xining 810001, People's Republic of China.
Wei Guan *Department of Respiratory Medicine, Qinghai University Affiliated Hospital, Xining 810001, People's Republic of China.ORCID 0000-0002-1080-0509
Qinghai University Affiliated Hospital · CNShenzhen University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe World Health Organization states that China had 0.9 million cases of tuberculosis in 2017, accounting for 9% of cases globally. Despite a decrease in the incidence and mortality of tuberculosis in China over time, development in choosing the appropriate prevention and control of TB is required. PURPOSE: The aim of this study was to evaluate the diagnostic significance of interleukin-27 in bronchoalveolar lavage fluids for pulmonary tuberculosis. MATERIALS AND

methodsEventually, 107 bronchoalveolar lavage fluids from patients were included in this study. The concentrations of interleukin-27 and adenosine deaminase were determined in bronchoalveolar lavage fluids using enzyme-linked immunosorbent assay.

resultsIt was found that the concentrations of interleukin-27 in bronchoalveolar lavage fluids of sputum-positive pulmonary tuberculosis group were significantly higher than those in sputum-negative pulmonary tuberculosis, lung cancer, and previous pulmonary tuberculosis groups, respectively (all

conclusionInterleukin-27 in bronchoalveolar lavage fluids is a sensitive and specific biomarker for the differential diagnosis of pulmonary tuberculosis from lung cancer and previous pulmonary tuberculosis.

Indexed as

adenosine deaminasebronchoalveolar lavage fluidinterleukin-27pulmonary tuberculosis

Identifiers

PMID31819557
PMCPMC6897056
OpenAlexW2991315792

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.