ReviewNeuropsychiatric disease and treatment2019
Empathy In Neurodegenerative Diseases: A Systematic Review.
Review in Neuropsychiatric disease and treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Empathy in Adults with Acquired Brain Injury: a Systematic Review and Meta-Analysis.Neuropsychology review · 2026Pooled it
- A systematic review of research on empathy in health care.Health services research · 2023Pooled it
- Empathy in primary progressive aphasia: Neural signatures and longitudinal trajectories.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Spousal Discrepancies in Perceived Needs of People Living with Alzheimer's Disease: A Mixed-Methods Study of Caregivers' Perspective Taking and Dyadic Communication.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026Article
- Social Cognition in Community Dwelling Persons With Dementia; Is Facial Emotion Recognition Related to Proxy Rated Empathy and Aggression?International journal of geriatric psychiatry · 2026Article
- Distinct neurostructural, cognitive, and neuropsychiatric associations of plasma p-tau217, and Aβ42/40 in Parkinson's disease and aging cohorts.Frontiers in aging neuroscience · 2026Article
- When the body resonates with the pain of the other: Empathy Bodyssence in Parkinson's disease.Neuroscience of consciousness · 2026Article
- The spectrum of embodied intersubjective synchrony in empathy: from fully embodied to externally oriented engagement in Parkinson's disease.Frontiers in psychology · 2025Article
- Exploring rodent prosociality: A conceptual framework.Translational neuroscience · 2025Review
- Necropolitics of Death in Neurodegeneration.Culture, medicine and psychiatry · 2024Review
- Grey-matter correlates of empathy in 4-Repeat Tauopathies.NPJ Parkinson's disease · 2023Article
- Cognitive empathy across the lifespan.Developmental medicine and child neurology · 2022Article
- Investigating the contribution of white matter hyperintensities and cortical thickness to empathy in neurodegenerative and cerebrovascular diseases.GeroScience · 2022Article
- Self-Oriented Empathy and Personality Organisation Level: Insights from a Psychiatric Sample.Clinical neuropsychiatry · 2022Article
- "I'm Never Going to Be in Phantom of the Opera": Relational and Emotional Wellbeing of Parkinson's Carers and Their Partners in and Beyond Dancing.Frontiers in psychology · 2021Article
- Enhanced Neural Empathic Responses in Patients with Spino-Bulbar Muscular Atrophy: An Electrophysiological Study.Brain sciences · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEmpathy, in its affective and cognitive components, is a crucial interpersonal ability. It is broadly studied in the field of psychopathology, whereas its study in the neurodegenerative diseases is relatively recent. Existing literature, though, focused on a reduced subset of considered diseases, which often found a compromise in empathy abilities. Organized knowledge about a more comprehensive set of diseases is lacking.
methodThe present PRISMA systematic review was aimed at collecting the current available literature concerning empathic alterations in adult patients affected by neurodegenerative diseases. It considered the different empathy components, evaluated existing patterns, the impact on patients' lives, and treatment considerations.
resultsOverall, the 32 retrieved studies describe a spread deterioration of empathic abilities in patients, with each disease displaying its own pattern of empathy functioning. Literature in this field is fragmented and of heterogeneous quality, and further studies are warranted to increase evidence of many preliminary results. DISCUSSION: In conclusion, we highlight the crucial importance of acknowledging empathy deficits in these diseases, showing their repercussion on both patients' and caregivers' quality of life, the establishment of a functional doctor-patient relationship, and the development of efficacious psychological intervention. These clinical approaches can be enriched by the knowledge of the spared abilities of patients affected by neurodegenerative diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.