Evidence map›Paper›PMID 31819439›Full record

ReviewInternational journal of nanomedicine2019

Relationship Between Structure And Antimicrobial Activity Of Zinc Oxide Nanoparticles: An Overview.

Bruna Lallo da Silva, Marina Paiva Abuçafy, Eloisa Berbel Manaia, João Augusto Oshiro Junior, Bruna Galdorfini Chiari-Andréo, Rosemeire Cl R Pietro, Leila Aparecida Chiavacci

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 473 citations in OpenAlex.

  1. Article
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  5. Green-SynthesizedBiomimetics (Basel, Switzerland) · 2026
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79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Bruna Lallo da SilvaDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, SP, Brazil.ORCID 0000-0002-0610-0833
Marina Paiva AbuçafyDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, SP, Brazil.ORCID 0000-0001-8247-2092
Eloisa Berbel ManaiaDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, SP, Brazil.ORCID 0000-0001-6352-1602
João Augusto Oshiro JuniorDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, SP, Brazil.ORCID 0000-0001-7247-1598
Bruna Galdorfini Chiari-AndréoDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, SP, Brazil.ORCID 0000-0001-7959-0207
Rosemeire Cl R PietroDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, SP, Brazil.ORCID 0000-0001-7859-8127
Leila Aparecida ChiavacciDepartment of Drugs and Medicines, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, SP, Brazil.ORCID 0000-0003-3128-3739
Universidade Estadual Paulista (Unesp) · BRCentro Universitário de Araraquara · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inappropriate use of antimicrobials has resulted in the selection of resistant strains. Thus, a great number of studies have focused on the investigation of new antimicrobial agents. The use of zinc oxide nanoparticles (ZnO NPs) to optimise the fight against microbial resistance has been receiving increased attention due to the non-specific activity of inorganic antimicrobial agents. The small particle size and the high surface area of ZnO NPs can enhance antimicrobial activity, causing an improvement in surface reactivity. In addition, surface modifiers covering ZnO NPs can play a role in mediating antimicrobial activity since the surface properties of nanomaterials alter their interactions with cells; this may interfere with the antimicrobial effect of ZnO NPs. The possibility of using surface modifiers with groups toxic to microorganisms can improve the antimicrobial activity of ZnO NPs. Understanding the exact toxicity mechanisms is crucial to elucidating the antimicrobial activity of ZnO NPs in bacteria and fungi. Therefore, this review aims to describe the mechanisms of ZnO NPs toxicity against fungi and bacteria and how the different structural and physical-chemical characteristics of ZnO NPs can interfere in their antimicrobial activity.

Indexed as

Anti-Infective AgentsBacteriaFungiMetal NanoparticlesStructure-Activity RelationshipZinc OxideAnti-Infective AgentsZinc Oxideantimicrobial activitynanoparticlestoxicity mechanismszinc oxide

Identifiers

PMID31819439
PMCPMC6897062
OpenAlexW2990628128

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.