ArticleInternational journal of chronic obstructive pulmonary disease2019
Critical Inhaler Handling Error Is an Independent Risk Factor for Frequent Exacerbations of Chronic Obstructive Pulmonary Disease: Interim Results of a Single Center Prospective Study.
Article in International journal of chronic obstructive pulmonary disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review of the effects of patient errors using inhaled delivery systems on clinical outcomes in COPD.BMJ open respiratory research · 2024Pooled it
- Diffusing capacity in chronic obstructive pulmonary disease assessment: A meta-analysis.Chronic respiratory diseasePooled it
- Effect of Gamification on Improved Adherence to Inhaled Medications in Chronic Obstructive Pulmonary Disease: Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- The effects of repeated inhaler device handling education in COPD patients: a prospective cohort study.Scientific reports · 2020Trial
- Determinants and Phenotypes of Poorly Controlled COPD Using the RADAR Score: A Cohort in Real-World Primary Care.Journal of clinical medicine · 2026Article
- Inhaled Medication Adherence Trajectory and Its Associated Factors in Patients with Chronic Obstructive Pulmonary Disease: A Group-Based Trajectory Modeling.Patient preference and adherence · 2026Article
- Beyond the Lungs: A Narrative Review of Cardiopulmonary Risk Reduction and Management Perspectives in Thai COPD Patients.International journal of chronic obstructive pulmonary disease · 2026Review
- Patient Burden and Insights in COPD: A Survey Analysis.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2025Article
- Inhaled Triple Therapy with Extrafine Single Inhaler Versus Multiple Devices in Chronic Obstructive Pulmonary Disease (TRIPOLI): A Post-Authorization Retrospective Study.International journal of chronic obstructive pulmonary disease · 2025Observational
- Bibliometric Analysis of the Current Landscape of Chronic Obstructive Pulmonary Disease (COPD) Nursing Interventions and Research.International journal of chronic obstructive pulmonary disease · 2025Article
- Analysis of the Current State of COPD Nursing Based on a Bibliometric Approach from the Web of Science.International journal of chronic obstructive pulmonary disease · 2024Article
- Breaking down barriers to COPD management in primary care: applying the updated 2023 Canadian Thoracic Society guideline for pharmacotherapy.Frontiers in medicine · 2024Review
- Risk Factors Associated with Misuse of Soft Mist Inhaler in Patients with Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2024Observational
- Does mixing inhaler devices lead to unchecked inhaler technique errors in patients with COPD? Findings from the cross-sectional observational MISMATCH study.BMJ open respiratory research · 2023Article
- Personalizing Selection of Inhaled Delivery Systems in Chronic Obstructive Pulmonary Disease.Annals of the American Thoracic Society · 2023Review
- Developing a novel tool to assess the ability to self-administer medication - A systematic evaluation of patients' video recordings in the ABLYMED study.Frontiers in medicine · 2023Article
- Assessment of Inhaler Satisfaction and Determinants of High Satisfaction Among Korean COPD Patients.Journal of Korean medical science · 2022Article
- Impact of Sex on Proper Use of Inhaler Devices in Asthma and COPD: A Systematic Review and Meta-Analysis.Pharmaceutics · 2022Review
- Developing a novel tool to assess the ability to self-administer medication in non-demented in-hospital patients: ABLYMED study protocol.BMC geriatrics · 2022Article
- The Impact of 52-Week Single Inhaler Device Triple Therapy versus Dual Therapy on the Mortality of COPD Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Life (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Chronic obstructive pulmonary disease (COPD) acute exacerbations are significant causes of morbidity and mortality. "Frequent exacerbator" phenotypes are considered a distinct subgroup and this phenotype has a negative effect on lung function, quality of life, activity, hospital admission, and mortality. We assess inhaler handling technique and adherence, and evaluate risk factors associated with frequent exacerbations in COPD patients. Methods: This study was a cross-sectional, case-control study. We prospectively enrolled 189 COPD patients from Yeungnam University Hospital from January 2018 to November 2018. Subjects were tested regarding their inhaler technique in face-to-face interviews with an advanced practice nurse of inhaler upon study entry. Frequency of moderate to severe COPD exacerbations were reviewed via electronic medical records during 12 months prior to study entry. Frequent exacerbations were defined as ≥2 moderate to severe exacerbations in the prior 12 months. Multivariate logistic regression was performed to identify risk factors for frequent exacerbations. Results: Among 189 COPD patients, 50 (26.5%) were frequent exacerbators. Based on univariate analyses, body mass index (BMI) < 25 kg/m Conclusion: Any critical error, BMI < 25 kg/m
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Registered trials
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