Evidence map›Paper›PMID 31819292›Full record

ArticleBulletin of the World Health Organization2019

Managing the transition from paediatric to adult care for HIV, Kenya.

Irene Njuguna, Kristin Beima-Sofie, Caren Mburu, Cyrus Mugo, Danae A Black, Jillian Neary, Janet Itindi, Alvin Onyango, Jennifer Slyker, Laura Oyiengo and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Bulletin of the World Health Organization, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Irene NjugunaKenyatta National Hospital, Research and Programs, P.O. Box 20723-00202, Nairobi, Kenya.
Kristin Beima-SofieDepartment of Global Health, University of Washington, Seattle, United States of America (USA).
Caren MburuDepartment of Pediatrics and Child Health, University of Nairobi, Nairobi, Kenya.
Cyrus MugoKenyatta National Hospital, Research and Programs, P.O. Box 20723-00202, Nairobi, Kenya.
Danae A BlackDepartment of Epidemiology, University of Washington, Seattle, USA.
Jillian NearyDepartment of Global Health, University of Washington, Seattle, United States of America (USA).
Janet ItindiKenya Medical Research Institute, Kisumu, Kenya.
Alvin OnyangoDepartment of Pediatrics and Child Health, University of Nairobi, Nairobi, Kenya.
Jennifer SlykerDepartment of Global Health, University of Washington, Seattle, United States of America (USA).
Laura OyiengoNational AIDS and STI Control Program, Ministry of Health, Nairobi, Kenya.
Grace John-StewartDepartment of Global Health, University of Washington, Seattle, United States of America (USA).
Dalton WamalwaDepartment of Pediatrics and Child Health, University of Nairobi, Nairobi, Kenya.
University of Nairobi · KEKenyatta National Hospital · KEKenya Medical Research Institute · KEMinistry of Health · KESeattle University · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
Scientific/Technical CoreP2CHD042828 · NICHD · UNIVERSITY OF WASHINGTON · PI Daniel T A Eisenberg · 2017 to 2026
$6.3M
Women and HIV: Translation of Research into Practice-WLHIV Post-Graduate Research FellowshipD43TW009783 · FIC · UNIVERSITY OF WASHINGTON · PI Elizabeth Anne BUKUSI, CAREY FARQUHAR · 2015 to 2026
$4.1M
Transitioning from Pediatric to Adult HIV Care in Kenya Administrative SupplementR01HD089850 · NICHD · UNIVERSITY OF WASHINGTON · PI JOHN-STEWART, GRACE C. · 2016 to 2020
$2.3M
Pediatric HIV-1 in Africa: Pathogenesis and ManagementK24HD054314 · NICHD · UNIVERSITY OF WASHINGTON · PI JOHN-STEWART, GRACE C. · 2006 to 2016
$1.2M
FIC NIH HHS D43 TW009783NIAID NIH HHS P30 AI027757NICHD NIH HHS K24 HD054314NICHD NIH HHS P2C HD042828NICHD NIH HHS R01 HD089850
6 · The paper itself

Abstract

Expansion of access to diagnosis and treatment for human immunodeficiency virus (HIV) and a high incidence of HIV infection in adolescence has resulted in a growing population of adolescents and young adults living with HIV. The prevalence of poor retention in care, insufficient viral suppression and loss to follow-up are higher among adolescents and young adults compared with other age groups. Poor outcomes could be attributed to psychosocial changes during adolescence, but also to poor transitional care from paediatric to adult HIV services. In many countries, transition processes remain poorly defined and unstructured, which may jeopardize treatment adherence and retention. We describe existing definitions of transition and transition frameworks, and key elements of transition as proposed by key national stakeholders in Kenya. Our consensus definition of transition is "a planned process by which adolescents and young adults living with HIV, and their caregivers, are empowered with knowledge and skills to enable them to independently manage their health." Transition should begin soon after disclosure of HIV status until an adolescent gains the necessary knowledge and skills and is willing to move to adult services, or by 25 years of age. Proposed key elements of transition are: target ages for milestone achievement; readiness assessment; caregiver involvement and communication with adult clinics; flexibility to return to adolescent or paediatric clinics; group transition; and considerations for adolescents with special needs. Retention in care, linkage to care and viral suppression are important markers of transition success. Proposed definitions and key elements could provide a framework for structuring transition programmes in other countries.

Indexed as

Health Knowledge, Attitudes, PracticeAdolescentAge FactorsCaregiversCommunicationContinuity of Patient CareFemaleHIV InfectionsHumansKenyaMaleTransition to Adult CareYoung Adult

Identifiers

PMID31819292
PMCPMC6883269
OpenAlexW2990491970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.