ArticleHypertension research : official journal of the Japanese Society of Hypertension2020
A novel indicator, childhood lipid accumulation product, is associated with hypertension in Chinese children and adolescents.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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11 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Diagnostic accuracy of anthropometric indices for discriminating elevated blood pressure in pediatric population: a systematic review and a meta-analysis.BMC pediatrics · 2022Pooled it
- Article
- The relationship between depression and lipid accumulation product: a population-based study.Frontiers in psychiatry · 2024Article
- Effect of lipid accumulation product on the development of hypertension among nondiabetic individuals in eastern China: A cross-sectional study.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Predicting hypertension by obesity- and lipid-related indices in mid-aged and elderly Chinese: a nationwide cohort study from the China Health and Retirement Longitudinal Study.BMC cardiovascular disorders · 2023Article
- Association of lipid accumulation product with type 2 diabetes mellitus, hypertension, and mortality: a systematic review and meta-analysis.Journal of diabetes and metabolic disorders · 2022Review
- Combining multiaspect factors to predict the risk of childhood hypertension incidence.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Relative children's lipid accumulation with hypertension in Chinese children and adolescents.BMC public health · 2021Article
- Performance of waist-to-height ratio as a screening tool for identifying cardiometabolic risk in children: a meta-analysis.Diabetology & metabolic syndrome · 2021Article
- Relative Children's Lipid Accumulation Product Is a Novel Indicator for Metabolic Syndrome.Frontiers in endocrinology · 2021Article
- Children's Lipid Accumulation Product Combining Visceral Adiposity Index is a Novel Indicator for Predicting Unhealthy Metabolic Phenotype Among Chinese Children and Adolescents.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
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11 authors at 1 institution in 1 country.
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Abstract
Childhood hypertension has become an important public health issue. This study explored a novel indicator, namely, childhood lipid accumulation product (CLAP), which is associated with hypertension among children and adolescents. A total of 683 children and adolescents aged 8-15 years were measured for body weight, height, waist circumference (WC), abdominal skinfold thickness (AST), triacylglycerol (TG), blood pressure, dietary behaviors, and physical activity time. The novel childhood lipid accumulation product (CLAP) was the product of WC, AST, and TG (CLAP = WC (cm) × AST (mm) × TG (mmol/L)). The logarithmic CLAP (LnCLAP), height, weight, WC, WHtR, BMI, AST, and TG were standardized for sex and age using the z-score method (standardized variables: SLnCLAP, Sheight, Sweight, SWC, SWHtR, SBMI, SAST, and STG). The results showed that the overall prevalence of hypertension was 11.6% (13.1% in boys and 9.7% in girls). SLnCLAP ≥ 1, Sweight ≥ 1, SWC ≥ 1, SWHtR ≥ 1, SBMI ≥ 1, SAST ≥ 1, and STG ≥ 1 increased the statistical risk of childhood hypertension (odds ratio values (95% CI) were 3.70 (2.22-6.16), 2.58 (1.50-4.43), 3.08 (1.84-5.15), 2.33 (1.38-3.93), 2.96 (1.72-5.29), 2.38 (1.41-4.70), and 2.40 (1.38-4.19), respectively). The area under the ROC curve (AUC) for CLAP was higher than that for weight, WC, WHtR, BMI, AST, and TG in the prediction of hypertension. In conclusion, this study showed that CLAP is a novel indicator associated with hypertension in children and adolescents and can more effectively predict childhood hypertension than weight, WC, WHtR, BMI, AST, and TG can.
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