Evidence map›Paper›PMID 31819053›Full record

ArticleNature communications2019

Permeability of membranes in the liquid ordered and liquid disordered phases.

An Ghysels, Andreas Krämer, Richard M Venable, Walter E Teague, Edward Lyman, Klaus Gawrisch, Richard W Pastor

Abstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

  1. Review
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  10. Review
  11. Myelin sheaths can act as compact temporary oxygen storage units as modeled by an electrical RC circuit model.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Article
  13. Validation of a Coarse-Grained Martini 3 Model for Molecular Oxygen.Journal of chemical theory and computation · 2025
    Article
  14. Article
  15. Atomic view of photosynthetic metabolite permeability pathways and confinement in synthetic carboxysome shells.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

An GhyselsCenter for Molecular Modeling, Ghent University, Technologiepark 46, 9052, Gent, Belgium. an.ghysels@ugent.be.ORCID http://orcid.org/0000-0003-0015-2605
Andreas KrämerLaboratory of Computational Biology, National Heart Lung Blood Institute, National Institutes of Health, Bethesda, MD, 20892, USA.ORCID http://orcid.org/0000-0002-7699-3083
Richard M VenableLaboratory of Computational Biology, National Heart Lung Blood Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
Walter E TeagueLaboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, 20892, USA.
Edward LymanDepartment of Physics and Astronomy and Department of Chemistry and Biochemistry, University of Delaware, Newark, 19716, DE, USA.
Klaus GawrischLaboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, 20892, USA.ORCID http://orcid.org/0000-0002-0841-1539
Richard W PastorLaboratory of Computational Biology, National Heart Lung Blood Institute, National Institutes of Health, Bethesda, MD, 20892, USA. pastorr@nhlbi.nih.gov.ORCID http://orcid.org/0000-0002-2454-5131

Funding

Breakthrough Molecular Dynamics Research via an Anton2 SupercomputerR01GM116961 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI BLOOD, PHILIP D. · 2016 to 2023
$3.0M
Effects of lipidomic diversity on GPCRR01GM120351 · NIGMS · UNIVERSITY OF DELAWARE · PI LYMAN, EDWARD RAY · 2017 to 2021
$1.6M
NIGMS NIH HHS R01 GM116961NIGMS NIH HHS R01 GM120351
6 · The paper itself

Abstract

The functional significance of ordered nanodomains (or rafts) in cholesterol rich eukaryotic cell membranes has only begun to be explored. This study exploits the correspondence of cellular rafts and liquid ordered (L

Indexed as

Cell Membrane Permeability1,2-DipalmitoylphosphatidylcholineCholesterolComputer SimulationDiffusionLipid BilayersOxygenPhosphatidylcholinesProbabilityThermodynamics1,2-Dipalmitoylphosphatidylcholine1,2-oleoylphosphatidylcholineCholesterolLipid BilayersOxygenPhosphatidylcholines

Identifiers

PMID31819053
PMCPMC6901538

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.