ArticleTranslational psychiatry2019
Structural brain abnormalities in children and adolescents with comorbid autism spectrum disorder and attention-deficit/hyperactivity disorder.
Article in Translational psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Methylphenidate Enhances Spontaneous Fluctuations in Reward and Cognitive Control Networks in Children With Attention-Deficit/Hyperactivity Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Trial
- Cerebellar Contributions to Cerebral Connectivity in Severe Mental Illness: A Developmental Cascade and Predictive-Modeling Framework with Autistic Disorder as the Focal Case.Brain sciences · 2026Review
- Linking Brain Morphometry to Psychometric Measures and Energy-Metabolic Biomarkers in Adults With Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2026Article
- Cerebellar purkinje cell dysfunction contributes to gait impairments in Shank3-mutant mice.Molecular autism · 2026Article
- Common and distinct changes of regional resting-state brain activity between high- and low-functioning autism spectrum disorder.BMC psychiatry · 2026Article
- Atypical development of white matter structural networks in children and adolescents with autism spectrum disorder: a graph theory study.Frontiers in neuroscience · 2026Article
- Overlapping and distinct intrinsic connectivity of hippocampal and triple networks in autistic individuals with and without a comorbid condition of ADHD.Frontiers in psychiatry · 2026Article
- Subcortical shape alterations in children with Noonan syndrome spectrum: insights into genotype-phenotype associations.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- White matter microstructure abnormalities in children experiencing neglect without other forms of maltreatment.Scientific reports · 2025Article
- Understanding heterogeneity in psychiatric disorders: A method for identifying subtypes and parsing comorbidity.Psychiatry and clinical neurosciences · 2025Article
- A Framework for Comparison and Interpretation of Machine Learning Classifiers to Predict Autism on the ABIDE Dataset.Human brain mapping · 2025Article
- Intermittent Fasting Improves Social Interaction and Decreases Inflammatory Markers in Cortex and Hippocampus.Molecular neurobiology · 2025Article
- Developmental functional brain network abnormalities in autism spectrum disorder comorbid with attention deficit hyperactivity disorder.European journal of pediatrics · 2025Article
- rTMS-induced neuroimaging changes measured with structural and functional MRI in autism.Frontiers in neuroscience · 2025Article
- Autism and comorbidity: insights from brain imaging studies.European child & adolescent psychiatry · 2024Article
- Gray matter asymmetry alterations in children and adolescents with comorbid autism spectrum disorder and attention-deficit/hyperactivity disorder.European child & adolescent psychiatry · 2024Article
- Association between Autism Spectrum Disorder, Trace Elements, and Intracranial Fluid Spaces.International journal of molecular sciences · 2024Article
- The Dynamical Biomarkers in Functional Connectivity of Autism Spectrum Disorder Based on Dynamic Graph Embedding.Interdisciplinary sciences, computational life sciences · 2024Article
- Heterogeneity and convergence across seven neuroimaging modalities: a review of the autism spectrum disorder literature.Frontiers in psychiatry · 2024Review
- The ability to maintain rhythm is predictive of ADHD diagnosis and profile.BMC psychiatry · 2023Article
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11 authors.
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Abstract
Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) share high rates of comorbidity, with the Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition now acknowledging the comorbid diagnosis of ASD and ADHD. Although structural abnormalities in the prefrontal cortex, cerebellum, and basal ganglia occur in both ASD and ADHD, no structural studies have focused exclusively on patients with comorbid ASD and ADHD. We thus aimed to clarify the structural features and developmental changes in patients with comorbid ASD and ADHD in a relatively large sample from two sites. Ninety-two patients were age-matched to 141 typically developing (TD) controls (age range: 5-16 years) and assessed for volumetric characteristics using structural magnetic resonance imaging (i.e. surface-based morphometry). While there were no significant differences in prefrontal cortex, cerebellum, and basal ganglia volumes, patients with ASD and ADHD exhibited significantly lower left postcentral gyrus volumes than TD controls. We observed significantly lower postcentral gyrus volumes exclusively in children and preadolescents, and not in adolescents. Our findings suggest that abnormal somatosensory, attributed to delayed maturation of the left postcentral gyrus, leads to the core symptoms experienced by patients with comorbid ASD and ADHD.
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