Evidence map›Paper›PMID 31818209›Full record

ArticleJournal of the American Heart Association2019

Associations Between Features of Nonstenosing Carotid Plaque on Computed Tomographic Angiography and Ischemic Stroke Subtypes.

Ashley Knight-Greenfield, Joel Jose Quitlong Nario, Amar Vora, Hediyeh Baradaran, Alex Merkler, Babak B Navi, Hooman Kamel, Ajay Gupta

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The role of non-stenosing carotid artery plaques in embolic stroke of undetermined source, is it a silent offender? A review of literature.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
    Review
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  6. Review
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  8. Observational
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ashley Knight-GreenfieldDepartment of Radiology Weill Cornell Medicine New York NY.
Joel Jose Quitlong NarioDepartment of Radiology Weill Cornell Medicine New York NY.
Amar VoraDepartment of Radiology Weill Cornell Medicine New York NY.
Hediyeh BaradaranDepartment of Radiology University of Utah Salt Lake City UT.
Alex MerklerDepartment of Radiology Weill Cornell Medicine New York NY.
Babak B NaviDepartment of Radiology Weill Cornell Medicine New York NY.
Hooman KamelDepartment of Radiology Weill Cornell Medicine New York NY.
Ajay GuptaDepartment of Radiology Weill Cornell Medicine New York NY.
Weill Cornell Medicine · USCornell University · USMIND Research Institute · USUniversity of Utah · US

Funding

MRI Detection of CarotId Plaques as a mecHanism for Embolic strokes of undeteRmined source (MRI DECIPHER)R01HL144541 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUPTA, AJAY, KAMEL, HOOMAN · 2019 to 2023
$3.9M
Left Atrial abNormality, ThromboEmbolism, and Race: Novel risk factors for stroke (LANTERN)R01NS097443 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI KAMEL, HOOMAN · 2016 to 2019
$1.5M
A Machine Learning Approach For CTA-based Plaque Characterization and Stroke Risk Prediction in Carotid Artery AtherosclerosisR21HL145427 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUPTA, AJAY, SABUNCU, MERT RORY · 2019 to 2020
$244k
NHLBI NIH HHS R01 HL144541NHLBI NIH HHS R21 HL145427NINDS NIH HHS R01 NS097443
6 · The paper itself

Abstract

Background Thromboembolism from nonstenosing carotid plaques may be an underrecognized cause of embolic strokes of undetermined source (ESUS). We evaluated the association between features of nonstenosing atherosclerotic plaque on computed tomographic angiography and ESUS. Methods and Results We identified consecutive acute ischemic stroke patients from 2011 to 2015 who had unilateral anterior territory infarction on brain magnetic resonance imaging and a neck computed tomographic angiography. We included ESUS cases and as controls, cardioembolic strokes. Patients with ≥50% internal carotid artery atherosclerotic stenosis ipsilateral to the stroke were excluded from this analysis. Reviewers blinded to infarct location and stroke cause retrospectively evaluated computed tomographic angiography studies for specific plaque features including thickness of the total, soft, and calcified plaque; presence of ulceration; and perivascular fat attenuation. Paired

Indexed as

Computed Tomography AngiographyAgedAged, 80 and overBrain IschemiaCarotid Artery DiseasesFemaleHumansMaleMiddle AgedPlaque, AtheroscleroticRetrospective StudiesStrokeacute strokecarotid arterycomputed tomography angiographyplaque

Identifiers

PMID31818209
PMCPMC6951053
OpenAlexW2994900396

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.