Evidence map›Paper›PMID 31818011›Full record

ArticleSensors (Basel, Switzerland)2019

A Graphene-Based Glycan Biosensor for Electrochemical Label-Free Detection of a Tumor-Associated Antibody.

Filip Kveton, Anna Blsakova, Lenka Lorencova, Monika Jerigova, Dusan Velic, Ola Blixt, Bo Jansson, Peter Kasak, Jan Tkac

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Reversible Lectin Binding to Glycan-Functionalized Graphene.International journal of molecular sciences · 2021
    Article
  3. Review
  4. Glycan Nanobiosensors.Nanomaterials (Basel, Switzerland) · 2020
    Review
  5. Applications of Graphene-Based Materials in Sensors.Sensors (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Filip KvetonDepartment of Glycobiotechnology, Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 38 Bratislava, Slovakia.
Anna BlsakovaDepartment of Glycobiotechnology, Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 38 Bratislava, Slovakia.
Lenka LorencovaDepartment of Glycobiotechnology, Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 38 Bratislava, Slovakia.
Monika JerigovaDepartment of Physical Chemistry, Faculty of Natural Sciences, Comenius University, Mlynska Dolina, 842 15 Bratislava, Slovakia.
Dusan VelicDepartment of Physical Chemistry, Faculty of Natural Sciences, Comenius University, Mlynska Dolina, 842 15 Bratislava, Slovakia.
Ola BlixtDepartment of Chemistry, University of Copenhagen, 1871 Copenhagen, Denmark.
Bo JanssonDivision of Oncology and Pathology, Department of Clinical Sciences, Lund, Lund University, Lund, SE 221 85, Sweden.
Peter KasakCenter for Advanced Materials, Qatar University, P.O. Box 2713, Doha, Qatar.ORCID 0000-0003-4557-1408
Jan TkacDepartment of Glycobiotechnology, Institute of Chemistry, Slovak Academy of Sciences, Dubravska cesta 9, 845 38 Bratislava, Slovakia.ORCID 0000-0002-0765-7262
Institute of Chemistry of the Slovak Academy of Sciences · SKInternational Laser Center · SKLund University · SEQatar University · QAUniversity of Copenhagen · DK

Funding

Agentúra Ministerstva Školstva, Vedy, Výskumu a Športu SR 2/0090/16Agentúra Ministerstva Školstva, Vedy, Výskumu a Športu SR 2/0137/18Agentúra na Podporu Výskumu a Vývoja APVV 17-0300European Regional Development Fund ITMS no.: 26240120007
6 · The paper itself

Abstract

The study describes development of a glycan biosensor for detection of a tumor-associated antibody. The glycan biosensor is built on an electrochemically activated/oxidized graphene screen-printed electrode (GSPE). Oxygen functionalities were subsequently applied for covalent immobilization of human serum albumin (HSA) as a natural nanoscaffold for covalent immobilization of Thomsen-nouvelle (Tn) antigen (GalNAc-

Indexed as

Antibodies, NeoplasmAntigens, Tumor-Associated, CarbohydrateBiosensing TechniquesElectrochemical TechniquesElectrodesGraphiteHumansLimit of DetectionSerum AlbuminAntibodies, NeoplasmAntigens, Tumor-Associated, CarbohydrateGraphiteSerum AlbuminTn antigenbiosensorelectrochemistryglycangraphene screen-printed electrodesTn antigen

Identifiers

PMID31818011
PMCPMC6960651
OpenAlexW2991861300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.