Evidence map›Paper›PMID 31817972›Full record

ReviewJournal of clinical medicine2019

Management of Acute Severe Colitis in the Era of Biologicals and Small Molecules.

Christine Verdon, Talat Bessissow, Peter L Lakatos

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Saudi Arabia consensus guidance for the diagnosis and management of adults with inflammatory bowel disease.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2022
    Article
  4. Tofacitinib: An Option for Acute Severe Ulcerative Colitis?GE Portuguese journal of gastroenterology · 2022
    Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christine VerdonDivision of Gastroenterology, McGill University Health Centre, Montreal, QC H3G 1A4, Canada.
Talat BessissowDivision of Gastroenterology, McGill University Health Centre, Montreal, QC H3G 1A4, Canada.ORCID 0000-0003-2610-1910
Peter L LakatosDivision of Gastroenterology, McGill University Health Centre, Montreal, QC H3G 1A4, Canada.ORCID 0000-0002-3948-6488

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute severe ulcerative colitis (ASUC) is a medical emergency which occurs in about 20%-30% of patients with ulcerative colitis during their lifetime, and does carry a mortality risk of 1%. The management of inflammatory bowel diseases has evolved with changes in objective patient monitoring, as well as the availability of new treatment options with the development of new biological and small molecules; however, data is limited regarding their use in the context of ASUC. This review aims to discuss the emerging data regarding biologicals and small molecules therapies in the context of ASUC.

Indexed as

acute severe ulcerative colitiscorticosteroidscyclosporineinfliximabsurgical managementtacrolimus

Identifiers

PMID31817972
PMCPMC6947608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.