Evidence map›Paper›PMID 31817885›Full record

ArticleAntibiotics (Basel, Switzerland)2019

Effect of a Herbal Therapy on Clinical Symptoms of Acute Lower Uncomplicated Urinary Tract Infections in Women: Secondary Analysis from a Randomized Controlled Trial.

Winfried Vahlensieck, Horst Lorenz, Anne Schumacher-Stimpfl, Roland Fischer, Kurt G Naber

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04032574 (Multicenter, Randomized, Double-blind, Placebo-controlled Parallel Group Trial to Evaluate the Efficacy and Tolerability of a Phytotherapy Combination), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04032574 phase3completednot on this map

Multicenter, Randomized, Double-blind, Placebo-controlled Parallel Group Trial to Evaluate the Efficacy and Tolerability of a Phytotherapy Combination (Aqualibra) in Patients With Uncomplicated Cystitis

TypeinterventionalSponsorMedice Arzneimittel Pütter GmbH & Co KGRan1991 to 1992Enrolled200ConditionsUrinary Tract Infection Lower AcuteArmsHerbal Medicinal Product, Placebo
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Winfried VahlensieckDepartment of Urology, Kurpark-Klinik, Kurstraße 41-45, 61231 Bad Nauheim, Germany.
Horst LorenzBBS-Büro für Biometrie und Statistik, Im Unterfeld 17, 63543 Neuberg, Germany.
Anne Schumacher-StimpflMedice Arzneimittel Pütter GmbH & Co. KG, Kuhloweg 37, 58638 Iserlohn, Germany.
Roland FischerMedice Arzneimittel Pütter GmbH & Co. KG, Kuhloweg 37, 58638 Iserlohn, Germany.
Kurt G NaberDepartment of Urology, Technical University of Munich, Urology, Ismaninger Str. 22, 81675 München, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methodsA secondary analysis was conducted with data from a randomized, controlled, double-blind trial comparing a fixed combination of extracts of restharrow root, Java tea, and goldenrod herb (Aqualibra

resultsBased on a subgroup of patients with evaluable microbiologic data (

conclusionsA fixed combination of extracts of restharrow root, Java tea, and goldenrod herb was superior to placebo regarding symptom relief and prevention of antibiotic use in women with lower uUTI.

trial registrationClinicalTrials.gov: NCT04032574.

Indexed as

ACSSAcute Cystitis Symptom Scoreherbal treatmentpatient-reported outcomessymptomatic treatmenturinary tract infection

Identifiers

PMID31817885
PMCPMC6963539

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.