Evidence map›Paper›PMID 31817876›Full record

ReviewJournal of clinical medicine2019

Bioresorbable Vascular Scaffolds-Dead End or Still a Rough Diamond?

Mateusz P Jeżewski, Michał J Kubisa, Ceren Eyileten, Salvatore De Rosa, Günter Christ, Maciej Lesiak, Ciro Indolfi, Aurel Toma, Jolanta M Siller-Matula, Marek Postuła

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mateusz P JeżewskiDepartment of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology, Medical University of Warsaw, 02091 Warsaw, Poland.
Michał J KubisaDepartment of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology, Medical University of Warsaw, 02091 Warsaw, Poland.
Ceren EyiletenDepartment of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology, Medical University of Warsaw, 02091 Warsaw, Poland.
Salvatore De RosaDepartment of Medical and Surgical Sciences, Division of Cardiology, "Magna Graecia" University, 88100 Catanzaro, Italy.ORCID 0000-0001-5388-942X
Günter ChristDepartment of Cardiology, 5th Medical Department with Cardiology, Kaiser Franz Josef Hospital, 31100 Vienna, Austria.
Maciej Lesiak1st Department of Cardiology, Poznan University of Medical Sciences, 1061701 Poznań, Poland.ORCID 0000-0003-2630-5016
Ciro IndolfiDepartment of Medical and Surgical Sciences, Division of Cardiology, "Magna Graecia" University, 88100 Catanzaro, Italy.
Aurel TomaDepartment of Internal Medicine II, Division of Cardiology, Medical University of Vienna, 231090 Vienna, Austria.ORCID 0000-0003-2522-3887
Jolanta M Siller-MatulaDepartment of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology, Medical University of Warsaw, 02091 Warsaw, Poland.
Marek PostułaDepartment of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology, Medical University of Warsaw, 02091 Warsaw, Poland.ORCID 0000-0002-7826-4458

Funding

European Union - the European Regional Development Fund Operational Program "Innovative economy" for 2007-2013
6 · The paper itself

Abstract

Percutaneous coronary interventions with stent-based restorations of vessel patency have become the gold standard in the treatment of acute coronary states. Bioresorbable vascular scaffolds (BVS) have been designed to combine the efficiency of drug-eluting stents (DES) at the time of implantation and the advantages of a lack of foreign body afterwards. Complete resolution of the scaffold was intended to enable the restoration of vasomotor function and reduce the risk of device thrombosis. While early reports demonstrated superiority of BVS over DES, larger-scale application and longer observation exposed major concerns about their use, including lower radial strength and higher risk of thrombosis resulting in higher rate of major adverse cardiac events. Further focus on procedural details and research on the second generation of BVS with novel properties did not allow to unequivocally challenge position of DES. Nevertheless, BVS still have a chance to present superiority in distinctive indications. This review presents an outlook on the available first and second generation BVS and a summary of results of clinical trials on their use. It discusses explanations for unfavorable outcomes, proposed enhancement techniques and a potential niche for the use of BVS.

Indexed as

acute coronary syndromeangioplastybioresorbable vascular scaffolddrug-eluting stentpercutaneous coronary intervention

Identifiers

PMID31817876
PMCPMC6947479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.