Evidence map›Paper›PMID 31817851›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Sex Differences in Glutathione Peroxidase Activity and Central Obesity in Patients with Type 2 Diabetes at High Risk of Cardio-Renal Disease.

Mia Steyn, Karima Zitouni, Frank J Kelly, Paul Cook, Kenneth A Earle

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Letter to Editor about Effect of DriedInternational journal of preventive medicine · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Mia SteynThomas Addison Unit: St George's University Hospitals NHS Foundation Trust, London SW17 0QT, UK.
Karima ZitouniInstitute of Infection and Immunity, St George's University of London, London SW17 0QT, UK.
Frank J KellyNIHR Health Protection Research Unit in Health Impact of Environmental Hazards, King's College London, London SE1 9NH, UK.ORCID 0000-0003-2558-8392
Paul CookChemical Pathology and Metabolic Medicine, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.
Kenneth A EarleThomas Addison Unit: St George's University Hospitals NHS Foundation Trust, London SW17 0QT, UK.
St George's, University of London · GBKing's College London · GBSt George’s University Hospitals NHS Foundation Trust · GBUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

Dialysis Clinic Inc C-3305Medical Research Council MR/S020810/1The National Institutes of Health Research UKCRN ID:8432.
6 · The paper itself

Abstract

Women with type 2 diabetes (T2DM) have an increased susceptibility of developing cardio-renal disease compared to men, the reasons and the mechanisms of this vulnerability are unclear. Since oxidative stress plays a key role in the development of cardio-renal disease, we investigated the relationship between sex, plasma antioxidants status (glutathione peroxidase (GPx-3 activity), vitamin E and selenium), and adiposity in patients with T2DM at high risk of cardio-renal disease. Women compared to men had higher GPx-3 activity (

Indexed as

antioxidantscardiovascular riskglutathione peroxidaseoxidative stresssex differencesType 2 diabetes

Identifiers

PMID31817851
PMCPMC6943424
OpenAlexW2991870127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.