Evidence map›Paper›PMID 31817799›Full record

ArticleJournal of clinical medicine2019

Pallidal Deep Brain Stimulation in DYT6 Dystonia: Clinical Outcome and Predictive Factors for Motor Improvement.

Annika Danielsson, Miryam Carecchio, Laura Cif, Anne Koy, Jean-Pierre Lin, Göran Solders, Luigi Romito, Katja Lohmann, Barbara Garavaglia, Chiara Reale and 8 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Voice and Speech in Deep Brain Stimulation in Dystonia: A Retrospective Study, Systematic Review, and Meta-Analysis.Movement disorders : official journal of the Movement Disorder Society · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. ArXiv · 2025
    Article
  7. Late-Onset Dystonia WithJournal of clinical neurology (Seoul, Korea) · 2023
    Article
  8. Generalized Dystonia Due to a PathogenicTremor and other hyperkinetic movements (New York, N.Y.) · 2023
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. GPi-DBS forMovement disorders clinical practice · 2022
    Review
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Annika DanielssonDepartment of Women's and Children's Health, Karolinska Institutet, 17176 Stockholm, Sweden.
Miryam CarecchioDepartment of Pediatric Neuroscience, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20131 Milan, Italy.
Laura CifDépartement de Neurochirurgie, Unité de Recherche sur les Comportements et Mouvements Anormaux, (URCMA), Centre hospitalier universitaire de Montpellier, 34090 Montpellier, France.
Anne KoyUniversity of Cologne, Faculty of Medicine and University Hospital Cologne, Deparment of Pediatrics, 50924 Cologne, Germany.
Jean-Pierre LinComplex Motor Disorders Services, Evelina London Children`s Hospital, Children's Neuromodulation, Children and Women's Health Institute, King's Health Partners, London SE1 7EH, UK.
Göran SoldersDepartment of Clinical Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden.
Luigi RomitoDepartment of Movement Disorders, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy.
Katja LohmannInstitute of Neurogenetics, University of Luebeck, 23562 Luebeck, Germany.
Barbara GaravagliaMedical Genetics and Neurogenetics Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20126 Milan, Italy.
Chiara RealeMedical Genetics and Neurogenetics Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20126 Milan, Italy.
Giovanna ZorziDepartment of Pediatric Neuroscience, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20131 Milan, Italy.
Nardo NardocciDepartment of Pediatric Neuroscience, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20131 Milan, Italy.
Philippe CoubesDépartement de Neurochirurgie, Unité de Recherche sur les Comportements et Mouvements Anormaux, (URCMA), Centre hospitalier universitaire de Montpellier, 34090 Montpellier, France.
Victoria GonzalezDépartement de Neurochirurgie, Unité de Recherche sur les Comportements et Mouvements Anormaux, (URCMA), Centre hospitalier universitaire de Montpellier, 34090 Montpellier, France.
Agathe RoubertieDépartement de Neuropédiatrie, Centre hospitalier universitaire de Montpellier, 34295 Montpellier, France.
Gwenaelle Collod-BeroudAix Marseille Univ, INSERM, MMG, 13385 Marseille, France.
Göran LindDepartment of Clinical Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden.
Kristina TedroffDepartment of Women's and Children's Health, Karolinska Institutet, 17176 Stockholm, Sweden.

Funding

Deutsche Forschungsgemeinschaft DFG; FOR2488, LO1553/9-1Linnea & Josef Carlssons stiftelse -Stockholms Läns Landsting SLL20150690
6 · The paper itself

Abstract

Pallidal deep brain stimulation is an established treatment in dystonia. Available data on the effect in DYT-THAP1 dystonia (also known as DYT6 dystonia) are scarce and long-term follow-up studies are lacking. In this retrospective, multicenter follow-up case series of medical records of such patients, the clinical outcome of pallidal deep brain stimulation in DYT-THAP1 dystonia, was evaluated. The Burke Fahn Marsden Dystonia Rating Scale served as an outcome measure. Nine females and 5 males were enrolled, with a median follow-up of 4 years and 10 months after implant. All benefited from surgery: dystonia severity was reduced by a median of 58% (IQR 31-62,

Indexed as

Burke Fahn Marsden Dystonia Rating ScaleDYT-THAP1 dystonialong-term follow-uppallidal deep brain stimulation

Identifiers

PMID31817799
PMCPMC6947218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.