Evidence map›Paper›PMID 31817657›Full record

ArticleSensors (Basel, Switzerland)2019

Competitive USB-Powered Hand-Held Potentiostat for POC Applications: An HRP Detection Case.

Yaiza Montes-Cebrián, Albert Álvarez-Carulla, Gisela Ruiz-Vega, Jordi Colomer-Farrarons, Manel Puig-Vidal, Eva Baldrich, Pere Ll Miribel-Català

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yaiza Montes-CebriánDepartment of Electronics and Biomedical Engineering, Faculty of Physics, Universitat de Barcelona, 08028 Barcelona, Spain.ORCID 0000-0001-5045-0067
Albert Álvarez-CarullaDepartment of Electronics and Biomedical Engineering, Faculty of Physics, Universitat de Barcelona, 08028 Barcelona, Spain.ORCID 0000-0001-5293-4487
Gisela Ruiz-VegaDiagnostic Nanotools Group, Cibbim-Nanomedicine, Vall Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.
Jordi Colomer-FarraronsDepartment of Electronics and Biomedical Engineering, Faculty of Physics, Universitat de Barcelona, 08028 Barcelona, Spain.
Manel Puig-VidalDepartment of Electronics and Biomedical Engineering, Faculty of Physics, Universitat de Barcelona, 08028 Barcelona, Spain.ORCID 0000-0002-6074-9246
Eva BaldrichDiagnostic Nanotools Group, Cibbim-Nanomedicine, Vall Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.ORCID 0000-0003-1393-215X
Pere Ll Miribel-CatalàDepartment of Electronics and Biomedical Engineering, Faculty of Physics, Universitat de Barcelona, 08028 Barcelona, Spain.ORCID 0000-0002-2715-6684

Funding

COORDINATING CENTER FOR THE CANCER GENETICS NETWORKU01CA078284 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI FINKELSTEIN, DIANNE M · 1998 to 2006
$6.0M
Secretaria d'Universitats i Recerca of Generalitat de Catalunya Grant 2017 SGR 240Spanish Ministry of Economy, Agencia Estatal de Investigación and Fondo Europeo de Desarrollo Regional (AEI/FEDER, UE) TEC2016-78284-C3-3-RSpanish Ministry of Economy, Agencia Estatal de Investigación, Fondo de Investigaciones Sanitarias of Instituto de Salud Carlos III (ISCIII) and Fondo Europeo de Desarrollo Regional (AEI/FEDER, UE) DTS17/00145
6 · The paper itself

Abstract

Considerable efforts are made to develop Point-of-Care (POC) diagnostic tests. POC devices have the potential to match or surpass conventional systems regarding time, accuracy, and cost, and they are significantly easier to operate by or close to the patient. This strongly depends on the availability of miniaturized measurement equipment able to provide a fast and sensitive response. This paper presents a low-cost, portable, miniaturized USB-powered potentiostat for electrochemical analysis, which has been designed, fabricated, characterized, and tested against three forms of high-cost commercial equipment. The portable platform has a final size of 10.5 × 5.8 × 2.5 cm, a weight of 41 g, and an approximate manufacturing cost of $85 USD. It includes three main components: the power module which generates a stable voltage and a negative supply, the front-end module that comprises a dual-supply potentiostat, and the back-end module, composed of a microcontroller unit and a LabVIEW-based graphic user interface, granting plug-and-play and easy-to-use operation on any computer. The performance of this prototype was evaluated by detecting chronoamperometrically horseradish peroxidase (HRP), the enzymatic label most widely used in electrochemical biosensors. As will be shown, the miniaturized platform detected HRP at concentrations ranging from 0.01 ng·mL

Indexed as

electrochemical biosensorhorseradish peroxidase (HRP) chronoamperometrylow-cost electronicsportablereconfigurable potentiostatUSB-powered

Identifiers

PMID31817657
PMCPMC6960634

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.