Evidence map›Paper›PMID 31817628›Full record

ArticleMolecules (Basel, Switzerland)2019

Are the Hydantoin-1,3,5-triazine 5-HT

Annamaria Lubelska, Gniewomir Latacz, Magdalena Jastrzębska-Więsek, Magdalena Kotańska, Rafał Kurczab, Anna Partyka, Małgorzata Anna Marć, Daria Wilczyńska, Agata Doroz-Płonka, Dorota Łażewska and 3 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Perspectives on obesity imaging: [International journal of obesity (2005) · 2025
    Article
  2. Article
  3. AR71, Histamine HInternational journal of molecular sciences · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Trisubstituted 1,3,5-Triazines as Histamine HMolecules (Basel, Switzerland) · 2023
    Article
  8. Guanidines: Synthesis of Novel Histamine HPharmaceuticals (Basel, Switzerland) · 2023
    Article
  9. Discovery of (Journal of medicinal chemistry · 2022
    Article
  10. Multitargeting the Action of 5-HTInternational journal of molecular sciences · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Annamaria LubelskaDepartment of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Cracow, Poland.
Gniewomir LataczDepartment of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Cracow, Poland.ORCID 0000-0001-9247-2598
Magdalena Jastrzębska-WięsekDepartment of Clinical Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Cracow, Poland.ORCID 0000-0002-5388-1214
Magdalena KotańskaDepartment of Pharmacodynamics, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Cracow, Poland.ORCID 0000-0002-3946-1192
Rafał KurczabDepartment of Medicinal Chemistry Maj Institute of Pharmacology, Polish Academy of Science, Smętna 12, PL 31-343 Cracow, Poland.
Anna PartykaDepartment of Clinical Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Cracow, Poland.ORCID 0000-0001-9606-5228
Małgorzata Anna MarćDepartment of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Cracow, Poland.ORCID 0000-0002-5183-801X
Daria WilczyńskaDepartment of Clinical Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Cracow, Poland.
Agata Doroz-PłonkaDepartment of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Cracow, Poland.
Dorota ŁażewskaDepartment of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Cracow, Poland.ORCID 0000-0001-8454-4440
Anna WesołowskaDepartment of Clinical Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Cracow, Poland.ORCID 0000-0003-2383-3278
Katarzyna Kieć-KononowiczDepartment of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Cracow, Poland.
Jadwiga HandzlikDepartment of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Cracow, Poland.

Funding

Narodowe Centrum Nauki UMO-2015/17/B/NZ7/02973 and UMO-2016/21/N/NZ7/03265 and UMO-2018/31/B/NZ7/02160
6 · The paper itself

Abstract

Though the 5-HT

Indexed as

AnimalsAnti-Obesity AgentsCaco-2 CellsHumansHydantoinsMaleMolecular StructureProtein BindingRats, WistarReceptors, SerotoninSerotonin AntagonistsStructure-Activity RelationshipTriazinesAnti-Obesity AgentsHydantoinsReceptors, Serotoninserotonin 6 receptorSerotonin AntagonistsTriazines1,3,5-triazine5-HT6R antagonistADME-Tox parametershydantoinobesityprocognitive effect

Identifiers

PMID31817628
PMCPMC6943527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.