Evidence map›Paper›PMID 31817569›Full record

ReviewMolecules (Basel, Switzerland)2019

Antidepressant Potential of Cinnamic Acids: Mechanisms of Action and Perspectives in Drug Development.

Lúcio Ricardo Leite Diniz, Marilia Trindade de Santana Souza, Joice Nascimento Barboza, Reinaldo Nóbrega de Almeida, Damião Pergentino de Sousa

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Neuropharmacology Potential of the Hydroalcoholic Extract from the Leaves ofEvidence-based complementary and alternative medicine : eCAM · 2023
    Article
  8. Review
  9. Methanolic Extract ofDrug design, development and therapy · 2022
    Article
  10. Article
  11. Article
  12. Myeloperoxidase Inhibitory and Antioxidant Activities of (Pharmaceuticals (Basel, Switzerland) · 2021
    Article
  13. Review
  14. Article
  15. Review
  16. Involvement of GABABioMed research international · 2021
    Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lúcio Ricardo Leite DinizDepartament of Pharmacy, Federal University of Sergipe, São Cristóvão SE 49100-000, Brazil.
Marilia Trindade de Santana SouzaDepartament of Pharmacy, Federal University of Sergipe, São Cristóvão SE 49100-000, Brazil.
Joice Nascimento BarbozaDepartament of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa PB 58051-970, Brazil.
Reinaldo Nóbrega de AlmeidaDepartment of Physiology and Pathology, Federal University of Paraíba, João Pessoa PB 58051-970, Brazil.
Damião Pergentino de SousaDepartament of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa PB 58051-970, Brazil.ORCID 0000-0002-7180-4896
Universidade Federal da Paraíba · BRUniversidade Federal de Sergipe · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is a health problem that compromises the quality of life of the world's population. It has different levels of severity and a symptomatic profile that affects social life and performance in work activities, as well as a high number of deaths in certain age groups. In the search for new therapeutic options for the treatment of this behavioral disorder, the present review describes studies on antidepressant activity of cinnamic acids, which are natural products found in medicinal plants and foods. The description of the animal models used and the mechanisms of action of these compounds are discussed.

Indexed as

AnimalsAntidepressive AgentsCinnamatesDepressionDisease Models, AnimalDrug DevelopmentAntidepressive AgentsCinnamatescinnamic acidbehavioral disordersdepressionforced swim testnatural productsphenolic acidsphenylpropanoidsplantstail suspension test

Identifiers

PMID31817569
PMCPMC6943791
OpenAlexW2994050832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.