Evidence map›Paper›PMID 31817529›Full record

ReviewGenes2019

Conversion of DNA Sequences: From a Transposable Element to a Tandem Repeat or to a Gene.

Ana Paço, Renata Freitas, Ana Vieira-da-Silva

Abstract readReview
In one paragraph

Review in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Satellite DNAs in Drosophila koepferae (repleta group) reveal patterns of origin, chromosomal organization, transcription, and turnover in the buzzatii cluster.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Satellite DNAs rising from the transposon graveyards.DNA research : an international journal for rapid publication of reports on genes and genomes · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Microsatellites explorer: A database of short tandem repeats across genomes.Computational and structural biotechnology journal · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Study of Dispersed Repeats in theInternational journal of molecular sciences · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ana PaçoMED-Mediterranean Institute for Agriculture, Environment and Development, University of Évora, 7002-554 Évora, Portugal.
Renata FreitasIBMC-Institute for Molecular and Cell Biology, University of Porto, R. Campo Alegre 823, 4150-180 Porto, Portugal.
Ana Vieira-da-SilvaMED-Mediterranean Institute for Agriculture, Environment and Development, University of Évora, 7002-554 Évora, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eukaryotic genomes are rich in repetitive DNA sequences grouped in two classes regarding their genomic organization: tandem repeats and dispersed repeats. In tandem repeats, copies of a short DNA sequence are positioned one after another within the genome, while in dispersed repeats, these copies are randomly distributed. In this review we provide evidence that both tandem and dispersed repeats can have a similar organization, which leads us to suggest an update to their classification based on the sequence features, concretely regarding the presence or absence of retrotransposons/transposon specific domains. In addition, we analyze several studies that show that a repetitive element can be remodeled into repetitive non-coding or coding sequences, suggesting (1) an evolutionary relationship among DNA sequences, and (2) that the evolution of the genomes involved frequent repetitive sequence reshuffling, a process that we have designated as a "DNA remodeling mechanism". The alternative classification of the repetitive DNA sequences here proposed will provide a novel theoretical framework that recognizes the importance of DNA remodeling for the evolution and plasticity of eukaryotic genomes.

Indexed as

Evolution, MolecularEukaryotaRetroelementsTandem Repeat SequencesRetroelementsdispersed sequencesDNA remodeling mechanismmobilization of tandem repeatsorigin of tandem repeatstandem repeats

Identifiers

PMID31817529
PMCPMC6947457

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.