Trial reportInternational journal of environmental research and public health2019
The Effects of Anterior Cruciate Ligament Reconstruction on Individual Quadriceps Muscle Thickness and Circulating Biomarkers.
Trial report in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Acute Effects of Open Kinetic Chain Exercise Versus Those of Closed Kinetic Chain Exercise on Quadriceps Muscle Thickness in Healthy Adults.International journal of environmental research and public health · 2020Trial
- Auditory-cued terminal knee extension enhances vastus medialis motor unit function in the early phase following ACL reconstruction: a randomized controlled trial.Knee surgery & related research · 2026Article
- Anterior cruciate ligament reconstruction is associated with increased corticospinal excitability and rate of force development.BMC sports science, medicine & rehabilitation · 2026Article
- Muscle atrophy following anterior cruciate ligament reconstruction: A narrative review.Histology and histopathology · 2026Review
- Isokinetic evaluation of knee muscles and correlation of maximum torque of the extensors of the operated knee with thigh circumference in soccer players 2 years after ACL reconstruction: A cross-sectional study.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2025Article
- Effects of neuromuscular electrical stimulation on neuromuscular function and muscle quality in patient following anterior cruciate ligament reconstruction.Journal of exercise rehabilitation · 2025Article
- Neurophysiology of ACL Injury.Orthopedic reviews · 2025Article
- Molecular biomarker approaches to prevention of post-traumatic osteoarthritis.Nature reviews. Rheumatology · 2024Review
- Article
- Sports activity level after ACL reconstruction is predicted by vastus medialis or vastus medialis obliquus thickness, single leg triple hop distance or 6-m timed hop, and quality of life score.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Article
- The temporal and spatial effects of reconstructive surgery on the atrophy of hindlimb muscles in anterior cruciate ligament transected rats.Physiological research · 2023Article
- Article
- Bilateral Comparisons of Quadriceps Thickness after Anterior Cruciate Ligament Reconstruction.Medicina (Kaunas, Lithuania) · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anterior cruciate ligament reconstruction (ACLR) frequently results in quadriceps atrophy. The present study investigated the effect of ACLR on the muscle thickness of the different constituent muscles of the quadriceps and circulating biomarkers related to muscle atrophy and hypertrophy. Fourteen subjects underwent anterior cruciate ligament reconstruction following injury. Quadriceps muscle thicknesses were measured using ultrasound, and circulating biomarkers in the blood were measured using enzyme-linked immunosorbent assays (ELISAs) at the preoperative visit (PRE) and at two postoperative visits (PO1, PO2) in the early stages post-surgery. Differences between time points were analyzed using one-way repeated measures analysis of variance (ANOVA) tests. The most important finding was that severe muscle atrophy occurred in the vastus intermedius (VI) after ACLR (PRE: 20.45 ± 6.82 mm, PO1: 16.05 ± 6.13 mm, PO2: 13.18 ± 4.7 mm, F = 59.0,
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