Evidence map›Paper›PMID 31817172›Full record

ArticleMolecules (Basel, Switzerland)2019

Ginseng Gintonin Enhances Hyaluronic Acid and Collagen Release from Human Dermal Fibroblasts Through Lysophosphatidic Acid Receptor Interaction.

Rami Lee, Na-Eun Lee, Hongik Hwang, Hyewhon Rhim, Ik-Hyun Cho, Seung-Yeol Nah

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. The regulatory role of Korean ginseng in skin cells.Journal of ginseng research · 2021
    Review
  8. Review
  9. Visualization of the Relationship Between Hyaluronic Acid and Wound Healing: A Bibliometric Analysis.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Rami LeeGinsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.
Na-Eun LeeGinsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.
Hongik HwangCenter for Neuroscience, Korea Institute of Science and Technology, Seoul 02792, Korea.
Hyewhon RhimCenter for Neuroscience, Korea Institute of Science and Technology, Seoul 02792, Korea.
Ik-Hyun ChoDepartment of Convergence Medical Science, Department of Science in Korean Medicine and Brain Korea 21 Plus Program, Graduate School, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0002-1036-0494
Seung-Yeol NahGinsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.
Konkuk University · KRKorea Institute of Science and Technology · KRKyung Hee University · KR

Funding

NRF of Korea funded by the Ministry of Science, ICT, and Future Planning for the Basic Science Research Program NRF 2017R1D1A1A09000520The Brain Research Program NRF2016M3C7A1913845
6 · The paper itself

Abstract

Gintonin is a newly discovered component of ginseng and acts as a ligand for G protein-coupled lysophosphatidic acid (LPA) receptors. It is currently unclear whether gintonin has skin-related effects. Here, we examined the effects of a gintonin-enriched fraction (GEF) on [Ca

Indexed as

CalciumCell ProliferationCell SurvivalCollagenDermisFibroblastsHumansHyaluronan SynthasesHyaluronic AcidPanaxPlant ExtractsReceptors, Lysophosphatidic AcidCalciumCollagengintoninHAS1 protein, humanHyaluronan SynthasesHyaluronic AcidPlant ExtractsReceptors, Lysophosphatidic Acidcollagenginsenggintoninhuman dermal fibroblasthuman skinhyaluronic acid

Identifiers

PMID31817172
PMCPMC6943507
OpenAlexW2994043286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.