Evidence map›Paper›PMID 31817135›Full record

ReviewInternational journal of molecular sciences2019

Calcium Signaling in ß-cell Physiology and Pathology: A Revisit.

Christiane Klec, Gabriela Ziomek, Martin Pichler, Roland Malli, Wolfgang F Graier

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 114 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The dietary calcium-to-magnesium ratio and its association with glycemic control in type 2 diabetes: a cross-sectional study.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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  10. Integrating network analysis and machine learning to elucidate chemical-induced pancreatic toxicity in zebrafish embryos.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Article
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Christiane KlecDivision of Oncology, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0003-0195-8280
Gabriela ZiomekMolecular Biology and Biochemistry, Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Neue Stiftingtalstraße 6/6, 8010 Graz, Austria.
Martin PichlerDivision of Oncology, Department of Internal Medicine, Medical University of Graz, 8036 Graz, Austria.
Roland MalliMolecular Biology and Biochemistry, Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Neue Stiftingtalstraße 6/6, 8010 Graz, Austria.ORCID 0000-0001-6327-8729
Wolfgang F GraierMolecular Biology and Biochemistry, Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Neue Stiftingtalstraße 6/6, 8010 Graz, Austria.ORCID 0000-0003-1871-3298
Medical University of Graz · AT

Funding

Austrian Science Fund FWF W 1226
6 · The paper itself

Abstract

Pancreatic beta (β) cell dysfunction results in compromised insulin release and, thus, failed regulation of blood glucose levels. This forms the backbone of the development of diabetes mellitus (DM), a disease that affects a significant portion of the global adult population. Physiological calcium (Ca

Indexed as

Calcium SignalingAnimalsDiabetes Mellitus, Type 2Endoplasmic ReticulumGolgi ApparatusHumansInsulin-Secreting CellsInsulin SecretionMitochondriaCa2+ signalingdiabetesinsulin secretionmitochondriaβ-cells

Identifiers

PMID31817135
PMCPMC6940736
OpenAlexW2993322797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.