ReviewPolymers2019
Core-Shell Fibers: Design, Roles, and Controllable Release Strategies in Tissue Engineering and Drug Delivery.
Review in Polymers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed.
- Pure Chitosan Microfluidic Spinning Affords Modular Core-Sheath Fibers and Hand-Crafted Scaffolds with Enhanced Fibroblast Compatibility.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Bioactive glass-based core-shell nanoparticles: Multifunctional platforms for controlled drug release and biomedical applications.Materials today. Bio · 2026Review
- Geometric Analysis and Modeling of Electrospun Nanofiber Mat Deposition in a Top-Down Vertical Configuration.Nanomaterials (Basel, Switzerland) · 2026Article
- Coaxial electrospinning of poly(ɛ-caprolactone)/gelatin core-shell biodegradable implants for localized delivery of metronidazole and dexamethasone for periodontal applications.Frontiers in bioengineering and biotechnology · 2026Article
- Non-Invasive Analysis of Bulk and Surface Remodeling of Non-Woven PLLA and Fiber-Sponge PLLA/Chitosan Scaffolds in Cell Culture Environment.Molecules (Basel, Switzerland) · 2025Article
- Engineering Nanoparticles and Bioscaffolds for Targeted microRNA Delivery in Cardiovascular Regeneration-A Comprehensive Review.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Review
- Beyond the shell: exploring polymer-lipid interfaces in core-shell nanofibers to carry hyaluronic acid and β-caryophyllene.Beilstein journal of nanotechnology · 2025Article
- Fiber Technology in Drug Delivery and Pharmaceuticals.Current drug delivery · 2025Review
- Core-Sheath Fibers via Single-Nozzle Spinneret Electrospinning of Emulsions and Homogeneous Blend Solutions.Materials (Basel, Switzerland) · 2024Review
- Article
- Wound Dressing with Electrospun Core-Shell Nanofibers: From Material Selection to Synthesis.Polymers · 2024Review
- Scattering integral equation formulation for intravascular inclusion biosensing.Scientific reports · 2024Article
- Stepwise degradable PGA-SF core-shell electrospinning scaffold with superior tenacity in wetting regime for promoting bone regeneration.Materials today. Bio · 2024Article
- Promoting osteogenesis and bone regeneration employing icariin-loaded nanoplatforms.Journal of biological engineering · 2024Review
- Electrospun Nanofibers Encapsulated with Natural Products: A Novel Strategy to Counteract Skin Aging.International journal of molecular sciences · 2024Article
- Multifunctional Electrospun Nanofibers for Biosensing and Biomedical Engineering Applications.Biosensors · 2023Review
- Encapsulation of Carbon Dots in a Core-Shell Mesh through Coaxial Direct Ink Writing for Improved Crop Growth.ACS sustainable chemistry & engineering · 2023Article
- Electrospun Fibers of Biocompatible and Biodegradable Polyesters, Poly(Ethylene Oxide) and Beeswax with Anti-Bacterial and Anti-Fungal Activities.Materials (Basel, Switzerland) · 2023Article
- Green Routes for Bio-Fabrication in Biomedical and Pharmaceutical Applications.Pharmaceutics · 2023Review
- Transforming Wound Management: Nanomaterials and Their Clinical Impact.Pharmaceutics · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The key attributes of core-shell fibers are their ability to preserve bioactivity of incorporated-sensitive biomolecules (such as drug, protein, and growth factor) and subsequently control biomolecule release to the targeted microenvironments to achieve therapeutic effects. Such qualities are highly favorable for tissue engineering and drug delivery, and these features are not able to be offered by monolithic fibers. In this review, we begin with an overview on design requirement of core-shell fibers, followed by the summary of recent preparation methods of core-shell fibers, with focus on electrospinning-based techniques and other newly discovered fabrication approaches. We then highlight the importance and roles of core-shell fibers in tissue engineering and drug delivery, accompanied by thorough discussion on controllable release strategies of the incorporated bioactive molecules from the fibers. Ultimately, we touch on core-shell fibers-related challenges and offer perspectives on their future direction towards clinical applications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.