Evidence map›Paper›PMID 31816959›Full record

ArticleMaterials (Basel, Switzerland)2019

New Pre-reacted Glass Containing Dental Composites (giomers) with Improved Fluoride Release and Biocompatibility.

Loredana Colceriu Burtea, Cristina Prejmerean, Doina Prodan, Ioana Baldea, Mihaela Vlassa, Miuta Filip, Marioara Moldovan, Madalina-Anca Lazar Moldovan, Aurora Antoniac, Vasile Prejmerean and 1 more

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Are flowable composite resins containing bioactive particles truly biocompatible?Journal of clinical and experimental dentistry · 2026
    Review
  3. Article
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  11. Expert consensus on early childhood caries management.International journal of oral science · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Water Sorption and Solubility of Flowable Giomers.Materials (Basel, Switzerland) · 2021
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Loredana Colceriu BurteaFaculty of Dentistry, Iuliu Hatieganu University of Medicine and Pharmacy, 8 Victor Babes Str., 400000 Cluj Napoca, Romania.
Cristina PrejmereanRaluca Ripan Institute of Research in Chemistry, Babes Bolyai University, 30 Fintanele Str., 400294 Cluj Napoca, Romania.
Doina ProdanRaluca Ripan Institute of Research in Chemistry, Babes Bolyai University, 30 Fintanele Str., 400294 Cluj Napoca, Romania.
Ioana BaldeaDepartment of Physiology, Iuliu Hatieganu University of Medicine and Pharmacy, 1 Clinicilor Str., 400006 Cluj Napoca, Romania.
Mihaela VlassaRaluca Ripan Institute of Research in Chemistry, Babes Bolyai University, 30 Fintanele Str., 400294 Cluj Napoca, Romania.
Miuta FilipRaluca Ripan Institute of Research in Chemistry, Babes Bolyai University, 30 Fintanele Str., 400294 Cluj Napoca, Romania.
Marioara MoldovanRaluca Ripan Institute of Research in Chemistry, Babes Bolyai University, 30 Fintanele Str., 400294 Cluj Napoca, Romania.
Madalina-Anca Lazar MoldovanDepartment of Oral and Cranio-Maxillofacial Surgery, Iuliu Hatieganu University of Medicine and Pharmacy, 33 Motilor Str, 40001 Cluj-Napoca, Romania.
Aurora AntoniacPhysical Metallurgy, Department of Metallic Materials Science, University Politehnica of Bucharest, 060042 Bucharest, Romania.
Vasile PrejmereanFaculty of Mathematics and Computer Science, Babes Bolyai University, 7-9 Universitatii Str., 400084 Cluj Napoca, Romania.
Ioana AmbrosieFaculty of Dentistry, Iuliu Hatieganu University of Medicine and Pharmacy, 8 Victor Babes Str., 400000 Cluj Napoca, Romania.
Babeș-Bolyai University · ROIuliu Hațieganu University of Medicine and Pharmacy · ROUniversitatea Națională de Știință și Tehnologie Politehnica București · RO

Funding

UEFISCDI PNII nr. 189/2012 (GIODENT)
6 · The paper itself

Abstract

The aim of the present work was to prepare a series of novel restorative giomers and investigate the morphology, the physico-chemical properties (residual monomer, fluoride release), and the cytotoxicity of the new materials. The experimental giomers were prepared as light-cured pastes by blending different resin matrices comprising aromatic/aliphatic/urethane (di) methacrylates, with hybrid fillers containing pre-reacted glasses (PRGs), a radiopaque glass, and nano fluorhydroxyapatite. Polyalkenoic acids based on acrylic acid/itaconic acid/N-acryloyl -L-leucine modified or not with methacrylic groups, together with a superficially active glass, were used to prepare the PRGs. The fluoride ion release of the experimental giomers was investigated within a period of 60 days of storage in bidistilled water while using a fluoride ion selective electrode. Beautifil II commercial product was used as a reference. Cell cytotoxicity tests were done in vitro, in accordance with ISO 10993-122012 proceedings. Human dermal fibroblasts and umbilical endothelial vein cultures were used. The values that were obtained for cumulative fluoride release for all experimental giomers were higher than for the Beautifil II product, being more than twice the ones that were obtained for the commercial product after 60 days of storage in bidistilled water. The experimental biomaterials showed similar and/or better results when compared to the commercial one; this effect was maintained in all tested conditions.

Indexed as

cytotoxicitydental giomersfluoride releaseresidual monomerSEM

Identifiers

PMID31816959
PMCPMC6926637
OpenAlexW2992704493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.