ArticleMolecules (Basel, Switzerland)2019
Optimizing Water-Based Extraction of Bioactive Principles of Hawthorn: From Experimental Laboratory Research to Homemade Preparations.
Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Evaluating the therapeutic potential of L-arginine and licorice extract in letrozole-induced polycystic ovary syndrome in rats: targeting interconnected molecular pathways.Scientific reports · 2026Article
- The Hawthorn (Foods (Basel, Switzerland) · 2026Review
- Optimization of Microwave-Assisted Extraction of Polyphenols fromAntioxidants (Basel, Switzerland) · 2025Article
- Bioactive Compounds from Banana Leaf Extracts: Influence of Extraction Methodologies and Their Integration into Knitted Hemp Fabrics.Materials (Basel, Switzerland) · 2024Article
- Ratanjot (Foods (Basel, Switzerland) · 2024Article
- Molecular changes in phenolic compounds inFrontiers in plant science · 2023Article
- Influence of Carbon Sources on the Phenolic Compound Production byBiomolecules · 2022Article
- Antimicrobial Screening and Fungicidal Properties ofPlants (Basel, Switzerland) · 2022Article
- Chemoprevention with a tea from hawthorn (Food chemistry: X · 2021Article
- Setup of an Ultrasonic-Assisted Extraction to Obtain High Phenolic Recovery inMolecules (Basel, Switzerland) · 2021Article
- Water-Based Extraction of Bioactive Principles from Blackcurrant Leaves andFoods (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Hawthorn (Crataegus) is used for its cardiotonic, hypotensive, vasodilative, sedative, antiatherosclerotic, and antihyperlipidemic properties. One of the main goals of this work was to find a well-defined optimized extraction protocol usable by each of us that would lead to repeatable, controlled, and quantified daily uptake of active components from hawthorn at a drinkable temperature (below 60 °C). A thorough investigation of the extraction mode in water (infusion, maceration, percolation, ultrasounds, microwaves) on the yield of extraction and the amount of phenolic compounds, flavonoids, and proanthocyanidin oligomers as well as on the Ultra High Performance Liquid Chromatography (UHPLC) profiles of the extracted compounds was carried out. High-resolution Fourier transform ion cyclotron resonance mass spectrometry was also implemented to discriminate the different samples and conditions of extraction. The quantitative and qualitative aspects of the extraction as well as the kinetics of extraction were studied, not only according to the part (flowers or leaves), the state (fresh or dried), and the granulometry of the dry plant, but also the stirring speed, the temperature, the extraction time, the volume of the container (cup, mug or bowl) and the use of infusion bags.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.