Evidence map›Paper›PMID 31816928›Full record

ArticleAntibiotics (Basel, Switzerland)2019

Anti-Tubercular Activity of Substituted 7-Methyl and 7-Formylindolizines and In Silico Study for Prospective Molecular Target Identification.

Katharigatta N Venugopala, Christophe Tratrat, Melendhran Pillay, Fawzi M Mahomoodally, Subhrajyoti Bhandary, Deepak Chopra, Mohamed A Morsy, Michelyne Haroun, Bandar E Aldhubiab, Mahesh Attimarad and 6 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
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  5. Journal of enzyme inhibition and medicinal chemistry · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Katharigatta N VenugopalaDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0003-0680-1549
Christophe TratratDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Melendhran PillayDepartment of Microbiology, National Health Laboratory Services, KZN Academic Complex, Inkosi Albert Luthuli Central Hospital, Durban 4001, South Africa.
Fawzi M MahomoodallyDepartment of Health Sciences, Faculty of Science, University of Mauritius, Réduit 80835 80832, Mauritius.ORCID 0000-0003-3962-8666
Subhrajyoti BhandaryDepartment of Chemistry, Indian Institute of Science Education and Research Bhopal, Indore By-pass Road, Bhauri, Bhopal 462 066, Madhya Pradesh, India.ORCID 0000-0002-0385-0604
Deepak ChopraDepartment of Chemistry, Indian Institute of Science Education and Research Bhopal, Indore By-pass Road, Bhauri, Bhopal 462 066, Madhya Pradesh, India.ORCID 0000-0002-0018-6007
Mohamed A MorsyDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0002-6752-9094
Michelyne HarounDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Bandar E AldhubiabDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0002-2684-4186
Mahesh AttimaradDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0002-7007-9119
Anroop B NairDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0003-2850-8669
Nagaraja SreeharshaDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0002-2058-255X
Rashmi VenugopalaDepartment of Public Health Medicine, University of KwaZulu-Natal, Howard College Campus, Durban 4001, South Africa.ORCID 0000-0002-1101-4577
Sandeep ChandrashekharappaInstitute for Stem Cell Biology and Regenerative Medicine, NCBS, TIFR, GKVK, Bellary Road, Bangalore 560 065, India.ORCID 0000-0003-2475-7270
Osama I AlwassilDepartment of Pharmaceutical Sciences, College of Pharmacy, King Saud bin Abdulaziz University for Health Sciences, Riyadh 11481 11543, Saudi Arabia.ORCID 0000-0002-6572-8321
Bharti OdhavDepartment of Biotechnology and Food Technology, Durban University of Technology, Durban 4001, South Africa.

Funding

Deanship of Scientific Research, King Faisal University 17122011
6 · The paper itself

Abstract

Novel series of diversely substituted indolizines were designed, synthesized, and evaluated for their in vitro anti-mycobacterial activity against H37Rv and multi-drug-resistant (MDR) strains of

Indexed as

indolizinesmolecular modelingmulti-component reactionmulti-drug resistanceMycobacterium tuberculosiswhole-cell anti-TB screening

Identifiers

PMID31816928
PMCPMC6963442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.